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Table 4 Recent studies on colistin for the treatment of ventilator-associated pneumonia (VAP)

From: Colistin for lung infection: an update

Year Prospective or retrospective Randomized controlled trial Studied patients with VAP Organism isolated Route of administration Country First author [reference]
2003 Prospective No 35 Acinetobacter baumanii IV Spain Garnacho-Montero [39]
2003 Prospective No 18 Pseudomonas aeruginosa IV USA Linden [40]
2003 Prospective No 15 P. aeruginosa, A. baumanii IV Greece Markou [41]
2006 Prospective No 9 P. aeruginosa, A. baumanii IV and AS Greece Falagas [42]
2006 Prospective No 16 A. baumanii AS Morocco Motaouakkil [43]
2007 Retrospective No 120 P. aeruginosa, A. baumanii IV Tunisia Kallel [44]
2007 Retrospective No 61 P. aeruginosa, A. baumanii IV Argentina Rios [45]
2008 Prospective Yes 28 A. baumanii IV Greece Betrosian [46]
2008 Retrospective No 10 A. baumanii IV Korea Song [47]
2008 Prospective No 8 P. aeruginosa IV and AS Greece Mastoraki [48]
2008 Prospective No 19 A. baumanii IV Italy Bassetti [49]
2008 Prospective No 60 P. aeruginosa, A. baumanii, Klebseilla pneumoniae AS Greece Michalopoulos [50]
2008 Prospective No 10 P. aeruginosa, A. baumanii IV Greece Markou [11]
2009 Retrospective No 9 P. aeruginosa, A. baumanii IV Turkey Tasbakan [51]
2009 Retrospective No 41 A. baumanii IV South Korea Jang [52]
2010 Retrospective No 86 P. aeruginosa, A. baumanii, K. pneumoniae IV and AS Greece Kofteridis [53]
2010 Retrospective No 121 P. aeruginosa, A. baumanii, K. pneumoniae IV and AS Greece Korbila [54]
2010 Prospective Yes 100 P. aeruginosa, A. baumanii, K. pneumonia, Escherichia coli AS Thailand Rattanaumpawan [55]
2010 Retrospective No 45 A. baumanii AS Taiwan Lin [56]
2010 Retrospective No 11 P. aeruginosa, A. baumanii, K. pneumonia, Enterobacter cloacae IV Greece Iosifidis [57]
2011 Retrospective No 15 A. baumanii AS Thailand Nakwan [58]
2011 Prospective No 15 A. baumanii IV and AS Spain Perez-Pedrero [59]
2011 Retrospective No 20 P. aeruginosa IV and AS Belgium Naesena [60]
2012 Prospective No 165 P. aeruginosa, A. baumanii AS France Lu [61]
2012 Retrospective No 36 A. baumanii IV Turkey Simsek [62]
2012 Retrospective No 45 A. baumanii IV and AS Turkey Kalin [63]
2013 Retrospective No 98 A. baumanii IV Israel Zalts [64]
2013 Retrospective No 208 P. aeruginosa, A. baumanii, K. pneumonia IV and AS Italy Tumbarello [65]
2013 Prospective Yes 43 A. baumanii IV Turkey Aydemir [66]
2013 Retrospective No 95 P. aeruginosa, A. baumanii, K. pneumonia IV and AS USA Doshi [67]
2013 Retrospective No 49 A. baumanii IV and AS Spain Garnacho-Montero [68]
2014 Retrospective No 82 A. baumanii IV Turkey Kalin [69]
2014 Retrospective No 26 A. baumanii AS Taiwan Hsieh [70]
2014 Retrospective No 130 A. baumanii IV Thailand Khawcharoenporn [71]
2014 Retrospective No 118 A. baumanii IV Taiwan Chuang [72]
2014 Retrospective No 141 A. baumanii, P. aeruginosa Enterobacteriaceae IV France Soubirou [73]
2014 Retrospective No 10 A. baumanii AS Korea Choi [74]
2014 Retrospective No 107 P. aeruginosa, A. baumanii IV Italy Petrosillo [75]
  1. IV intravenous, AS aerosolized.