Table 4 Recent studies on colistin for the treatment of ventilator-associated pneumonia (VAP)
Year | Prospective or retrospective | Randomized controlled trial | Studied patients with VAP | Organism isolated | Route of administration | Country | First author [reference] |
|---|---|---|---|---|---|---|---|
2003 | Prospective | No | 35 | Acinetobacter baumanii | IV | Spain | Garnacho-Montero [39] |
2003 | Prospective | No | 18 | Pseudomonas aeruginosa | IV | USA | Linden [40] |
2003 | Prospective | No | 15 | P. aeruginosa, A. baumanii | IV | Greece | Markou [41] |
2006 | Prospective | No | 9 | P. aeruginosa, A. baumanii | IV and AS | Greece | Falagas [42] |
2006 | Prospective | No | 16 | A. baumanii | AS | Morocco | Motaouakkil [43] |
2007 | Retrospective | No | 120 | P. aeruginosa, A. baumanii | IV | Tunisia | Kallel [44] |
2007 | Retrospective | No | 61 | P. aeruginosa, A. baumanii | IV | Argentina | Rios [45] |
2008 | Prospective | Yes | 28 | A. baumanii | IV | Greece | Betrosian [46] |
2008 | Retrospective | No | 10 | A. baumanii | IV | Korea | Song [47] |
2008 | Prospective | No | 8 | P. aeruginosa | IV and AS | Greece | Mastoraki [48] |
2008 | Prospective | No | 19 | A. baumanii | IV | Italy | Bassetti [49] |
2008 | Prospective | No | 60 | P. aeruginosa, A. baumanii, Klebseilla pneumoniae | AS | Greece | Michalopoulos [50] |
2008 | Prospective | No | 10 | P. aeruginosa, A. baumanii | IV | Greece | Markou [11] |
2009 | Retrospective | No | 9 | P. aeruginosa, A. baumanii | IV | Turkey | Tasbakan [51] |
2009 | Retrospective | No | 41 | A. baumanii | IV | South Korea | Jang [52] |
2010 | Retrospective | No | 86 | P. aeruginosa, A. baumanii, K. pneumoniae | IV and AS | Greece | Kofteridis [53] |
2010 | Retrospective | No | 121 | P. aeruginosa, A. baumanii, K. pneumoniae | IV and AS | Greece | Korbila [54] |
2010 | Prospective | Yes | 100 | P. aeruginosa, A. baumanii, K. pneumonia, Escherichia coli | AS | Thailand | Rattanaumpawan [55] |
2010 | Retrospective | No | 45 | A. baumanii | AS | Taiwan | Lin [56] |
2010 | Retrospective | No | 11 | P. aeruginosa, A. baumanii, K. pneumonia, Enterobacter cloacae | IV | Greece | Iosifidis [57] |
2011 | Retrospective | No | 15 | A. baumanii | AS | Thailand | Nakwan [58] |
2011 | Prospective | No | 15 | A. baumanii | IV and AS | Spain | Perez-Pedrero [59] |
2011 | Retrospective | No | 20 | P. aeruginosa | IV and AS | Belgium | Naesena [60] |
2012 | Prospective | No | 165 | P. aeruginosa, A. baumanii | AS | France | Lu [61] |
2012 | Retrospective | No | 36 | A. baumanii | IV | Turkey | Simsek [62] |
2012 | Retrospective | No | 45 | A. baumanii | IV and AS | Turkey | Kalin [63] |
2013 | Retrospective | No | 98 | A. baumanii | IV | Israel | Zalts [64] |
2013 | Retrospective | No | 208 | P. aeruginosa, A. baumanii, K. pneumonia | IV and AS | Italy | Tumbarello [65] |
2013 | Prospective | Yes | 43 | A. baumanii | IV | Turkey | Aydemir [66] |
2013 | Retrospective | No | 95 | P. aeruginosa, A. baumanii, K. pneumonia | IV and AS | USA | Doshi [67] |
2013 | Retrospective | No | 49 | A. baumanii | IV and AS | Spain | Garnacho-Montero [68] |
2014 | Retrospective | No | 82 | A. baumanii | IV | Turkey | Kalin [69] |
2014 | Retrospective | No | 26 | A. baumanii | AS | Taiwan | Hsieh [70] |
2014 | Retrospective | No | 130 | A. baumanii | IV | Thailand | Khawcharoenporn [71] |
2014 | Retrospective | No | 118 | A. baumanii | IV | Taiwan | Chuang [72] |
2014 | Retrospective | No | 141 | A. baumanii, P. aeruginosa Enterobacteriaceae | IV | France | Soubirou [73] |
2014 | Retrospective | No | 10 | A. baumanii | AS | Korea | Choi [74] |
2014 | Retrospective | No | 107 | P. aeruginosa, A. baumanii | IV | Italy | Petrosillo [75] |