Table 1 Study results

Fluid balance & urine output

  Mean output/24 h

2,920 ± 1,172.1

3,672.5 ± 1,353.7

n.s.

[21]

  Net balance at day 3

-5,480 mL

-1,490

<0.01

[20]

Hemodynamic measurements

  ΔCI at day 3

-0.1

0.2

n.s.

[20]

  ΔMAP at day 3

-1.5

0.6

n.s.

[20]

  Fluid boluses needed

11

35

Not reported

[20]

Oxygenation measurements

  ΔPaO₂/FIO₂ at 24 h

43

-24

<0.01

[20]

Serum albumin

  Increase in albumin at day 3

13 g/L

3 g/dL

<0.001

[20]

Colloid osmotic pressure

  Increase in COP at day 3

6.7

2.1

<0.01

[20]

  Rate of furosemide infusion at day 5 (mg/h)

4.9

6.7

<0.005

[20]

Ventilator-free days

  30 day follow-up

5.5

1

n.s.

[20]

ICU mortality

  Total mortality in ICU

7 (35%)

9 (45%)

n.s.

[20]