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Table 5 Comparison of clinical outcome data for patients with and without thrombocytopenia

From: Thrombocytopenia in adult patients with sepsis: incidence, risk factors, and its association with clinical outcome

Variable

Thrombocytopenia

No thrombocytopenia

P value

 

(n= 145)

(n= 159)

 

Major bleeding, n (%)

21 (14.4)

6 (3.7)

0.001*

PRBC transfusion, n (%)

85 (58.6)

62 (38.9)

0.0006*

FFP transfusion, n (%)

24 (16.5)

15 (9.4)

0.06

Platelet transfusion, n (%)

16 (11.3)

0

<0.0001*

Cryoprecipitate transfusion, n (%)

8 (5.5)

0

0.002*

Acute kidney injury (worst RIFLE stage ‘injury’ or more), n (%)

64 (44.1)

47 (29.5)

0.008*

Vasopressor duration (h), median (IQR)

37 (17–76)

23 (13–46)

0.004*

ALI/ARDS, n (%)

33 (22.8)

29 (18.2)

0.32

Mechanical ventilation, n (%)

75 (51.7)

78 (49.1)

0.64

Mechanical ventilation duration (days), median (IQR)

5.1 (2.1–9.2)

3 (1.1–9.2)

0.11

ICU length of stay (days), median (IQR)

3.1 (1.6–7.8)

2.1 (1.2–4.4)

0.001*

ICU mortality, n (%)

24 (16.5)

19 (11.9)

0.25

28-day mortality, n (%)

47 (32.4)

39 (24.5)

0.12

  1. PRBC, packed red blood cells; FFP, fresh frozen plasma; RIFLE, risk of renal dysfunction, injury to the kidney, failure of kidney function, loss of kidney function and end-stage kidney disease; IQR, interquartile range; ALI, acute lung injury; ARDS, acute respiratory distress syndrome; ICU, intensive care unit. * Significant P values.