Skip to main content

Table 5 Comparison of clinical outcome data for patients with and without thrombocytopenia

From: Thrombocytopenia in adult patients with sepsis: incidence, risk factors, and its association with clinical outcome

Variable Thrombocytopenia No thrombocytopenia P value
  (n= 145) (n= 159)  
Major bleeding, n (%) 21 (14.4) 6 (3.7) 0.001*
PRBC transfusion, n (%) 85 (58.6) 62 (38.9) 0.0006*
FFP transfusion, n (%) 24 (16.5) 15 (9.4) 0.06
Platelet transfusion, n (%) 16 (11.3) 0 <0.0001*
Cryoprecipitate transfusion, n (%) 8 (5.5) 0 0.002*
Acute kidney injury (worst RIFLE stage ‘injury’ or more), n (%) 64 (44.1) 47 (29.5) 0.008*
Vasopressor duration (h), median (IQR) 37 (17–76) 23 (13–46) 0.004*
ALI/ARDS, n (%) 33 (22.8) 29 (18.2) 0.32
Mechanical ventilation, n (%) 75 (51.7) 78 (49.1) 0.64
Mechanical ventilation duration (days), median (IQR) 5.1 (2.1–9.2) 3 (1.1–9.2) 0.11
ICU length of stay (days), median (IQR) 3.1 (1.6–7.8) 2.1 (1.2–4.4) 0.001*
ICU mortality, n (%) 24 (16.5) 19 (11.9) 0.25
28-day mortality, n (%) 47 (32.4) 39 (24.5) 0.12
  1. PRBC, packed red blood cells; FFP, fresh frozen plasma; RIFLE, risk of renal dysfunction, injury to the kidney, failure of kidney function, loss of kidney function and end-stage kidney disease; IQR, interquartile range; ALI, acute lung injury; ARDS, acute respiratory distress syndrome; ICU, intensive care unit. * Significant P values.