Limitations of global end-diastolic volume index as a parameter of cardiac preload in the early phase of severe sepsis: a subgroup analysis of a multicenter, prospective observational study

Table 1 Characteristics of patients with ALI/ARDS secondary to sepsis on the day of enrollment

Characteristics	SIMD group	Non-SIMD group	p value
Characteristics	n = 23	n = 70	p value
Age, years	79 (64–83)	72 (62–82)	0.430
Gender (male), n (%)	15 (65.2)	42 (60.0)	0.806
Septic shock, n (%)	14 (60.9)	40 (57.1)	0.899
Vasoactive-inotropic agents, n (%)	21 (91.3)	50 (71.4)	0.087
APACHE II score, points	24 (19–27)	25 (19–30)	0.565
SOFA score, points	12 (10–14)	11 (9–13)	0.345
PaO₂/FIO₂ ratio, mmHg	128 (80–198)	134 (96–185)	0.943
GEDI, mL/m²	757 (644–892)	837 (669–934)	0.293
EVLWi, mL/kg	16.2 (13.2–21.5)	18.2 (14.2–23.6)	0.287
PVPI	2.9 (2.4–3.7)	3.1 (2.4–3.9)	0.599
28-day mortality, n (%)	9 (39.1)	32 (45.7)	0.635

All data are presented as median (interquartile range) unless otherwise stated. ALI/ARDS acute lung injury/acute respiratory distress syndrome, APACHE Acute Physiology and Chronic Health Evaluation, SIMD sepsis-induced myocardial dysfunction, SOFA Sequential Organ Failure Assessment, GEDI global end-diastolic volume index, EVLWi extravascular lung water index, PVPI pulmonary vascular permeability index.

ISSN: 2052-0492