Fig. 2From: The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulationMicrothrombosis in the microcirculation in sepsis model of rat. Rat mesenteric microcirculation was observed under the intravital microscope after lipopolysaccharide injection. Round stiff leukocytes adhered to the unsmooth and swelled endothelial cells. Some leukocytes transmigrated to the extravascular space. Aggregated platelets stick to the leukocytes and endothelium and form leukocyte–platelet aggregation. Along with these changes, the blood flow gradually decreasedBack to article page