Table 1 Baseline clinical characteristics of survivors and non-survivors in the post-resuscitation phase of septic shock

Age, years

38 ± 15

34 ± 13

41 ± 16

0.00*

Gender, female, n (%)

36 (41)

14 (39)

22 (42)

0.83

 Medical

80 (91)

35 (44)

45 (56)

0.75

 Surgical

8 (9)

1 (12)

7 (88)

0.15

 Lung disease

46 (52)

14 (39)

32 (61)

0.05

 Renal disease

36 (41)

12 (33)

24 (46)

0.27

Comorbid illness, n (%)

34 (39)

14 (41)

20 (59)

1.0

 Diabetes mellitus

20 (23)

8 (40)

12 (60)

1.0

 Hypertension

10 (11)

4 (40)

6 (60)

1.0

 APACHE-II

16.5 ± 7.1

14.6 ± 7.0

17.9 ± 6.9

0.02*

 SOFA

10.2 ± 4.5

10.1 ± 4.2

10.3 ± 4.7

0.02*

 Hemoglobin, g/dl

10.2 ± 6.5

9.1 ± 2.2

10.9 ± 8.2

0.19

 TLC, ×10³/μL

17.9 ± 9.5

19 ± 12.1

17.2 ± 7.2

0.06

 Platelet, ×10³/μL

143 ± 132

160 ± 148

130 ± 97

0.13

 Serum creatinine, mg/dl

5.5 ± 2.8

2.4 ± 2.5

7.6 ± 2.6

0.17

 Blood urea nitrogen, mg/dl

54.8 ± 42.2

45.1 ± 28.3

61.3 ± 48.4

0.02*

 Total bilirubin, mg/dl

4.0 ± 3.5

2.7 ± 1.4

5.3 ± 3.6

0.00*

 ALT, U/L

142 ± 130

167 ± 102

124 ± 111

0.37

 AST, U/L

160 ± 130

185.4 ± 106.8

141.9 ± 103.5

0.23

 ALP, U/L

274 ± 100

353.6 ± 182.1

215.4 ± 136.4

0.47

 Albumin, g/dl

2.9 ± 0.7

3.1 ± 0.9

2.7 ± 0.4

0.00*

 Heart rate, bpm

103 ± 20

100 ± 19

105 ± 22

0.07

 MAP, mmHg

87 ± 9

89 ± 11

85 ± 8

<0.001**

 CVP, mmHg

8 ± 4

8 ± 3

9 ± 4

0.00*

 Central venous O₂ saturation, %

73 ± 7

73 ± 6

73 ± 8

0.82

 Lactate, mg/dl

18 ± 11

15.9 ± 9

18.9 ± 12.8

0.01*

 pH

7.36 ± 0.08

7.38 ± 0.05

7.35 ± 0.10

<0.001**

 Base excess

2.4 ± 2.3

1.5 ± 1.3

3.2 ± 2.7

0.00*

 Base deficit

4.1 ± 3.4

4.5 ± 3.5

3.9 ± 3.4

0.64

 PaO₂, mmHg

103 ± 26

104 ± 26

103 ± 26

0.02*

 PaCO₂, mmHg

42 ± 13

39 ± 7

44 ± 16

0.00*

 cHCO₃

23.6 ± 5

23 ± 4.1

24 ± 5.6

0.35

 Na⁺, mEq/L

140 ± 8.8

139 ± 10

140 ± 7.8

0.25

 K⁺, mEq/L

4.9 ± 1.6

5.5 ± 0.4

4.4 ± 0.5

0.36

 Cl⁻, mEq/L

101 ± 6.4

100 ± 6.9

102 ± 6.1

0.57

 Invasive ventilation, n (%)

76 (88)

30 (43)

46 (57)

0.54

 PaO₂/FiO₂ ratio

251 ± 95

254 ± 70

248 ± 109

<0.001**

 Pressure support, cmH₂O

17 ± 5

17 ± 3

17 ± 6

0.04*

 PEEP, cmH₂O

8 ± 3

9 ± 2

8 ± 3

0.45

 Tidal volume, ml

420 ± 91

459 ± 63

395 ± 97

0.02*

 Last 24 h, ml

1163 ± 940

1418 ± 1028

1009 ± 868

0.60

 Positive balance, n (%)

60 (68)

20 (33)

40 (67)

0.19

 Negative balance, n (%)

20 (23)

10 (50)

10 (50)

 Previous 24 h, ml

1461 ± 1058

1658 ± 987

1325 ± 1094

0.16

 Unaided, n (%)

50 (57)

22 (44)

28 (56)

0.58

 Lasix aided, n (%)

14 (16)

4 (29)

10 (71)

 Dialysis, n (%)

14 (16)

6 (43)

8 (57)

 Vasopressors, n (%)

88 (100)

36 (44)

52 (56)

0.16

 Vasopressin, n (%)

28 (32)

6 (21)

22 (79)

0.02*

 NADR dose, μg/kg/min

0.2 ± 0.1

0.10 ± 0.12

0.26 ± 0.26

<0.001**

 NADR ≥0.1 μg/kg/min

44 (50)

8 (18)

36 (82)

<0.001**

 Dobutamine, n (%)

6 (7)

4 (67)

2 (33)

0.22

 Ventilation

9 ± 8.5

15.7 ± 15

3.9 ± 6.3

<0.001**

 Vasopressor

16.4 ± 15.6

31.4 ± 30.1

5.2 ± 3.7

<0.001**

 RRT

21.1 ± 17

32.5 ± 30.5

12.6 ± 11.2

0.06

Length of ICU stay, days

21 ± 21

33.4 ± 30.9

12.1 ± 9.3

0.04*