Serum TNF-α (pg/ml, n = 7) | Serum HMGB-1 (ng/ml, n = 7) | Serum IL-10 (pg/ml, n = 7) | Serum BUN | Serum creatinine | |
---|---|---|---|---|---|
(mg/dl, n = 7) | |||||
Control | 39.5 (36.0–47.0) | 19.8 (19.0–23.4) | 59.5 (48.8–62.9) | 29.6 (27.2–30.7) | 0.11 (0.10–0.12) |
LPS | 2738.0 (2429.7–3377.2)** | 169.8 (166.7–224.5)** | 1361.0 (1256.3–1603.9)** | 98.8 (95.3–102.8)** | 0.35 (0.34–0.38)** |
LPS + T-5224 | 1533.0 (1453.9–1602.6)**,## | 132.8 (119.1–140.6)**,## | 3165.0 (2897.8–3400.8)**,## | 70.5 (68.4–76.8)**,## | 0.28 (0.22–0.29)**,## |
T-5224 | 32.0 (30.0–34.0) | 19.4 (17.9–21.1) | 64.9 (55.6–70.1) | 28.0 (24.0–28.7) | 0.10 (0.09–0.11) |