Skip to main content

Table 1 ISTH overt DIC, JAAM DIC, and SIC scoring systems

From: The pathophysiology, diagnosis, and management of sepsis-associated disseminated intravascular coagulation

Item

Score

ISTH overt DIC

JAAM DIC

ISTH SIC

Range

Range

Range

Platelet count

(× 109/L)

3

 − 

 < 80 or

≧ 50% decrease within 24 h

 − 

2

 < 50

 − 

 < 100

1

≧ 50, < 100

120 > , 80 ≦ or

≧ 30% decrease within 24 h

≧ 100, < 150

FDP

(D-dimer)

3

strong increase

≧ 25 μg/mL

(use convert chart)

 − 

2

moderate increase

 − 

 − 

1

 − 

≧ 10, < 25 μg/mL

(use convert chart)

 − 

Prothrombin time

2

≧ 6 s

 − 

 > 1.4

1

≧ 3 s, < 6 s

≧ 1.2 (PT ratio)

 > 1.2, ≦ 1.4

(PT-INR)

Fibrinogen (g/mL)

1

 < 100

 − 

 − 

SIRS score

1

 − 

 > 3

 − 

SOFA score

2

 − 

 − 

≧2

1

 − 

 − 

1

Total score for DIC or SIC

 

≧ 5

≧ 4

≧ 4

  1. Total SOFA score is the sum of 4 items (respiratory SOFA, cardiovascular SOFA, hepatic SOFA, and renal SOFA)
  2. ISTH International Society on Thrombosis and Haemostasis, DIC disseminated intravascular coagulation, JAAM Japanese Society for Acute Medicine, SIC sepsis-induced coagulopathy, SIRS systemic inflammatory response syndrome, SOFA Sequential Organ Failure Assessment