Univariable OR (95% CI) | P value | Multivariable OR (95% CI) | P value | |
---|---|---|---|---|
Preoperative visit | 0.44 (0.23–0.83) | 0.011 | 0.29 (0.13–0.64) | < 0.01 |
Characteristics at baseline | ||||
Age ≥ 75 years old | 1.56 (0.84–2.87) | 0.16 | ||
Male | 0.57 (0.31–1.06) | 0.076 | ||
Body mass index per 1 point increase | 0.88 (0.80–0.97) | < 0.01 | 0.92 (0.82–1.02) | 0.11 |
Left ventricular ejection fraction < 50% | 1.99 (1.04–3.80) | 0.037 | 1.56 (0.72–3.38) | 0.26 |
Chronic kidney disease (eGFR < 60) | 2.25 (1.11–4.55) | 0.024 | 0.93 (0.38–2.28) | 0.88 |
FEV1.0 < 70%a | 2.44 (1.21–4.92) | 0.013 | 1.47 (0.64–3.37) | 0.36 |
%VC < 80%a | 1.65 (0.89–3.05) | 0.11 | ||
Diabetes mellitus | 0.97 (0.51–1.84) | 0.92 | ||
History of smoking | 1.04 (0.56–1.92) | 0.90 | ||
Any cerebrovascular or mental illness | 1.66 (0.76–3.60) | 0.20 | ||
Previous cardiac surgery | 5.18 (2.14–12.6) | < 0.01 | 3.08 (1.06–8.97) | 0.039 |
EuroSCORE II per 1 point increase | 1.27 (1.15–1.41) | < 0.01 | 1.21 (1.06–1.38) | < 0.01 |
Characteristics during surgery | ||||
Median full sternotomy | 2.07 (0.87–4.89) | 0.096 | ||
Transcatheter surgery | 0.92 (0.36–2.37) | 0.86 | ||
Operation time per 1 h increase | 1.28 (1.06–1.54) | < 0.01 | 1.17 (0.95–1.46) | 0.14 |
Cardiopulmonary bypass use | 1.81 (0.93–3.50) | 0.080 | ||
rScO2 minimum per 1% increaseb | 0.95 (0.92–0.98) | < 0.01 | 0.96 (0.92–0.99) | 0.032 |
Transfusion received | 2.45 (1.09–5.52) | 0.030 | 0.99 (0.36–2.77) | 0.99 |
Highest plasma lactate level ≥ 2.0 mmol/l | 1.71 (0.92–3.18) | 0.088 |