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Table 4 NRI and IDI for assessing the contributions of different biomarkers for non-recovery prediction when combing with clinical model

From: Analysis of urinary C–C motif chemokine ligand 14 (CCL14) and first-generation urinary biomarkers for predicting renal recovery from acute kidney injury: a prospective exploratory study

Models

NRI (%)

p value

IDI (%)

p value

[TIMP-2] × [IGFBP7] + clinical model vs. clinical model

10.7

0.042

8.0

0.003

CCL14 + clinical model vs. clinical model

3.8

0.568

3.2

0.033

CCL14 + [TIMP-2] ×  [IGFBP7] + clinical model vs. clinical model

9.7

0.231

9.2

0.007

  1. NRI net reclassification improvement, IDI integrated discrimination improvement, TIMP-2 tissue inhibitor of metalloproteinases-2, IGFBP-7 insulin-like growth factor-binding protein 7, CCL14 C–C motif chemokine ligand 14