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Table 5 Recommendations for acute respiratory distress syndrome in major guidelines: (2) adjunctive therapies

From: Guideline-based management of acute respiratory failure and acute respiratory distress syndrome

 

JRS/JSICM/JSRCM-GL2021

SSCG2021

SRLF-GL 2019

FICM/ICS- GL 2018

SSAI-ARDS-GL2016

KSCCM/KATRD-ARDS-GL2016

CIRCI-GL2017

Restrictive fluid management

B

  

B

B

  

Pharmacotherapy

       

Corticosteroids

A (1–2 mg/kg)

  

C

E

D

B

Neutrophil elastase inhibitor

D

      

Beta2-agonists

E

   

E

  

NO inhalation

D

 

C

D

E

E

 

Thrombomodulin

–

      

ECMO

B: Severe

B: V-V, severe

A: V-V

B: Severe

 

B

 

Early rehabilitation

B: ≤ 72 h

      

No or light sedation

B

    

A

 

Omega-3 fatty acids enteral nutrition

B

      
  1. A, strongly recommended; B, weakly/conditionally recommended; C, expert opinion/research recommendation; D, weakly/conditionally not recommended; E, strongly not recommended; -, no recommendation
  2. ECMO extracorporeal membrane oxygenation, V-V veno-venous