Predictive value of soluble CD59 for poor 28-day neurological prognosis and all-cause mortality in patients after cardiopulmonary resuscitation: a prospective observatory study

Table 4 Areas under the curve (AUC) of various parameters for predicting 28-day all-cause mortality

	AUC	Standard error	95% CI
sCD59_D1	0.768	0.058	0.649–0.861
sCD59_D3	0.891	0.045	0.769–0.962
sCD59_D7	0.829	0.068	0.679–0.928
NSE_D1	0.798	0.056	0.683–0.885
NSE_D3	0.826	0.058	0.691–0.919
NSE_D7	0.807	0.069	0.653–0.913
S100β_D1	0.806	0.052	0.693–0.892
S100β_D3	0.851	0.053	0.720–0.937
S100β_D7	0.841	0.064	0.693–0.936
APACHE II_D1	0.812	0.062	0.699–0.897
APACHE II_D3	0.861	0.054	0.732–0.943
APACHE II_D7	0.899	0.049	0.764–0.971
CPR time	0.779	0.059	0.662–0.870
sCD59_D1 + NSE_D1	0.883^Aa	0.043	0.798–0.968
sCD59_D3 + NSE_D3	0.937^Bb	0.034	0.870–1.000
sCD59_D7 + NSE_D7	0.925^Cc	0.053	0.820–1.000
sCD59_D1 + S100β_D1	0.881^Dd	0.043	0.796–0.966
sCD59_D3 + S100β_D3	0.983^Ee	0.013	0.957–1.000
sCD59_D7 + S100β_D7	0.896^Ff	0.052	0.794–0.998
sCD59_D1 + APACHE II_D1	0.848^G	0.051	0.749–0.947
sCD59_D3 + APACHE II_D3	0.965^Hh	0.021	0.923–1.000
sCD59_D7 + APACHE II_D7	0.944^Ii	0.032	0.881–1.000

^A P = 0.023 (Z = 2.276) vs sCD59_D1; ^B P = 0.022 (Z = 2.285) vs sCD59_D3; ^C P = 0.041 (Z = 1.953) vs sCD59_D7; ^D P = 0.002 (Z = 2.431) vs sCD59_D1; ^E P = 0.023 (Z = 2.275) vs sCD59_D3; ^F P = 0.045 (Z = 1.101) vs sCD59_D7; ^G P = 0.031 (Z = 1.600) vs sCD59_D1; ^H P = 0.026 (Z = 2.234) vs sCD59_D3; ^I P = 0.046 (Z = 1.991) vs sCD59_D7; ^a P = 0.045 (Z = 1.998) vs NSE_D1; ^b P = 0.005 (Z = 2.813) vs NSE_D3; ^c P = 0.037 (Z = 1.809) vs NSE_D7; ^d P = 0.046 (Z = 1.857) vs S100β_D1; ^e P = 0.006 (Z = 2.712) vs S100β_D3; ^f P = 0.032 (Z = 1.199) vs S100β_D7; ^h P = 0.026 (Z = 2.217) vs APACHE II_D3; ⁱ P = 0.031 (Z = 1.442) vs APACHE II_D7
APACHE II Acute Physiology and Chronic Health Evaluation, APACHE II_D1 APACHE II on day 1 after ROSC, APACHE II_D3 APACHE II on day 3 after ROSC, APACHE II_D7 APACHE II on day 7 after ROSC, CI confidence interval, CPR cardiopulmonary resuscitation, NSE neuron-specific enolase, NSE_D1 NSE on day 1 after ROSC, NSE_D3 NSE on day 3 after ROSC, NSE_D7 NSE on day 7 after ROSC, ROSC restoration of spontaneous circulation, sCD59 soluble CD59, sCD59_D1 sCD59 on day 1 after ROSC, sCD59_D3 sCD59 on day 3 after ROSC, sCD59_D7 sCD59 on day 7 after ROSC, S100β soluble protein 100β, S100β_D1 S100β on day 1 after ROSC, S100β_D3 S100β on day 3 after ROSC, S100β_D7 S100β on day 7 after ROSC

ISSN: 2052-0492