Predictive value of soluble CD59 for poor 28-day neurological prognosis and all-cause mortality in patients after cardiopulmonary resuscitation: a prospective observatory study

Table 3 Areas under the curve (AUC) of various parameters for predicting poor 28-day neurological prognosis

	AUC	Standard error	P value	95% CI
sCD59_D1	0.746	0.092	0.007	0.554–0.886
sCD59_D3	0.862	0.067	0.000	0.687–0.960
sCD59_D7	0.778	0.087	0.001	0.588–0.908
NSE_D1	0.769	0.063	0.000	0.650–0.862
NSE_D3	0.845	0.055	0.000	0.713–0.932
NSE_D7	0.807	0.067	0.000	0.654–0.913
S100β_D1	0.813	0.055	0.000	0.701– 0.898
S100β_D3	0.874	0.049	0.000	0.747–0.951
S100β_D7	0.844	0.064	0.000	0.697–0.938
APACHE II_D1	0.770	0.083	0.001	0.653–0.864
APACHE II_D3	0.780	0.065	0.000	0.639–0.886
APACHE II_D7	0.833	0.064	0.000	0.684–0.931
CPR time	0.787	0.061	0.000	0.671–0.877
sCD59_D1 + NSE_D1	0.799^Aa	0.082	0.005	0.613–0.922
sCD59_D3 + NSE_D3	0.955^Bb	0.034	0.000	0.811–0.997
sCD59_D7 + NSE_D7	0.857^Cc	0.069	0.000	0.681–0.957
sCD59_D1 + S100β_D1	0.862^Dd	0.068	0.000	0.687–0.960
sCD59_D3 + S100β_D3	0.960^Ee	0.030	0.000	0.817–0.998
sCD59_D7 + S100β_D7	0.920^Ff	0.049	0.000	0.761–0.987
sCD59_D1 + APACHE II_D1	0.808^Gg	0.082	0.000	0.623–0.928
sCD59_D3 + APACHE II_D3	0.853^Hh	0.069	0.000	0.676–0.955
sCD59_D7 + APACHE II_D7	0.862^Ii	0.067	0.000	0.687–0.960

^A P = 0.027 (Z = 1.110) vs sCD59_D1; ^B P = 0.044 (Z = 1.854) vs sCD59_D3; ^C P = 0.040 (Z = 1.959) vs sCD59_D7; ^D P = 0.041 (Z = 2.040) vs sCD59_D1; ^E P = 0.045 (Z = 2.001) vs sCD59_D3; ^F P = 0.036 (Z = 2.101) vs sCD59_D7; ^G P = 0.009 (Z = 1.658) vs sCD59_D1; ^H P = 0.030 (Z = 2.167) vs sCD59_D3; ^I P = 0.031 (Z = 1.016) vs sCD59_D7; ^a P = 0.047 (Z = 1.783) vs NSE_D1; ^b P = 0.006 (Z = 1.857) vs NSE_D3; ^c P = 0.047 (Z = 2.876) vs NSE_D7; ^d P = 0.006 (Z = 2.758) vs S100β_D1; ^e P = 0.017 (Z = 1.752) vs S100β_D3; ^f P = 0.013 (Z = 2.487) vs S100β_D7; ^g P = 0.009 (Z = 1.658) vs APACHE II_D1; ^h P = 0.030 (Z = 2.167) vs APACHE II_D3; ⁱ P = 0.014 (Z = 2.455) vs APACHE II_D7
APACHE II Acute Physiology and Chronic Health Evaluation, APACHE II_D1 APACHE II on day 1 after ROSC, APACHE II_D3 APACHE II on day 3 after ROSC, APACHE II_D7 APACHE II on day 7 after ROSC, CI confidence interval, CPR cardiopulmonary resuscitation, NSE neuron-specific enolase, NSE_D1 NSE on day 1 after ROSC, NSE_D3 NSE on day 3 after ROSC, NSE_D7 NSE on day 7 after ROSC, ROSC restoration of spontaneous circulation, sCD59 soluble CD59, sCD59_D1 sCD59 on day 1 after ROSC, sCD59_D3 sCD59 on day 3 after ROSC, sCD59_D7 sCD59 on day 7 after ROSC, S100β soluble protein 100β, S100β_D1 S100β on day 1 after ROSC, S100β_D3 S100β on day 3 after ROSC, S100β_D7 S100β on day 7 after ROSC

ISSN: 2052-0492