| Healthy volunteers | Survivors | Non-survivors |
---|---|---|---|
(n = 20) | (n = 23) | (n = 45) | |
Age (years) | 58.4 ± 13.6 | 58.5 ± 16.1 | 65.0 ± 15.3 |
Male sex [n (%)] | 12 (60.0%) | 17 (73.9%) | 28 (62.2%) |
Comorbidities [n (%)] | Â | Â | Â |
 Hypertension | – | 9 (39.1%) | 22 (48.9%) |
 Diabetes | – | 5 (21.8%) | 12 (26.7%) |
 Coronary heart disease | – | 11 (47.8%) | 18 (40.0%) |
 Chronic pulmonary disease | – | 3 (13.0%) | 4 (8.8%) |
 Chronic renal disease | – | 2 (8.7%) | 5 (11.1%) |
Episode location [n (%)] | Â | Â | Â |
 OHCA | – | 14 (60.9%) | 34 (75.6%) |
 IHCA | – | 9 (39.1%) | 11 (24.4%) |
Causes of cardiac arrest [n (%)] | Â | Â | Â |
 Cardiac | – | 11 (47.8%) | 20 (44.4%) |
 Respiratory | – | 4 (17.4%) | 10 (22.2%) |
 Cerebral | – | 3 (13.1%) | 8 (17.8%) |
 Others | – | 5 (21.7%) | 7 (15.6%) |
Causes of death [n (%)] | Â | Â | Â |
 Instability or re-arrest | – | – | 12 (26.7%) |
 Brain death | – | – | 11 (24.4%) |
 Multiple organ dysfunction | – | – | 9 (20.0%) |
 Refractory cardiogenic shock | – | – | 8 (17.7%) |
 Respiratory failure | – | – | 3 (6.7%) |
 Heart failure | – | – | 2 (4.5%) |
Initial cardiac rhythm [n (%)] | Â | Â | Â |
 Shockable rhythm | – | 14 (60.9%) | 18 (40.0%) |
 Non-shockable rhythm | – | 9 (39.1%) | 27 (60.0%) |
CPR time (min) | – | 7.0 (3.0, 10.0) | 15.0 (8.0, 23.0)a |
Length of ICU-stay (days) | – | 10.0 (6.0, 17.0) | 5.0 (2.0, 11.5)a |
Treatments [n (%)] | Â | Â | Â |
 Ventilator use | – | 23 (100%) | 45 (100%) |
 Sedation | – | 23 (100%) | 45 (100%) |
 Hemodynamic support | – | 20 (87.0%) | 45 (100%) |
 Seizure treatment | – | 4 (17.4%) | 9 (20.0%) |
Laboratory findings | Â | Â | Â |
 Leukocyte count (× 109/L) | 6.66 (5.55, 8.45) | 12.46 (8.34, 19.32)b | 12.99 (9.81, 22.37)b |
 PCT (ng/mL) | 0.06 (0.03, 0.09) | 1.36 (0.81, 1.74)b | 2.00 (1.00, 3.47)b |
 hs-troponin I (μg/L) | 0.01 (0.00, 0.02) | 0.10 (0.06, 1.70)b | 0.87 (0.38, 6.80)b |
 BNP (pg/mL) | 26.5 (17.8, 37.8) | 124.0 (49.0, 370.9)b | 659.0 (183.0, 1994.7)a |
 Lactate (mmol/L) | 0.50 (0.25, 1.29) | 2.00 (1.40, 4.70)b | 6.40 (2.60, 11.70)a |
 Creatinine (μmol/L) | 70.4 (61.8, 76.9) | 83.0 (60.0, 106.0)b | 149.0 (100.3, 243.5)a |
APACHE II scores | – | 20.0 (14.0, 38.0) | 38.0 (34.0, 41.5)a |
SOFA scores | – | 5.0 (4.0, 7.5) | 10.0 (9.0, 13.0)a |