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Table 3 Factors associated with mortality in the Cox proportional hazards analysis

From: Descriptive statistics and risk factor analysis of children with community-acquired septic shock

Variables

Hazard ratio (95% CI)

p

Age

 < 1 year

Reference

 

 1–5 years

1.90 (1.33–2.70)

< 0.001

 6–19 years

0.92 (0.62–1.36)

0.679

Underlying conditions

 Care-dependence

0.57 (0.41–0.80)

< 0.01

 Neuromuscular

1.29 (0.90–1.85)

0.17

 Cardiovascular

0.89 (0.58–1.36)

0.59

 Hematological/malignancy/transplant

0.67 (0.35–1.28)

0.22

 Congenital/genetic

1.09 (0.55–2.7)

0.81

 Respiratory

1.04 (0.47–2.28)

0.92

Septic shock as admission diagnosis

0.96 (0.72–1.27)

0.76

Impaired consciousness

 Mild

Reference

 

 Moderate

0.98 (0.56–1.73)

0.95

 Severe

1.49 (1.09–2.02)

0.01

Transported from other hospitals

0.71 (0.53–0.97)

0.03

Admitted to accredited ICU

0.52 (0.38–0.70)

< 0.001

Hospital volume

 1–2

1.94 (1.36–2.76)

< 0.001

 3–6

1.26 (0.89–1.79)

0.19

 7–28

Reference

 

Therapies within three days of hospitalization

 Mechanical ventilation

3.26 (2.00–5.30)

< 0.001

 Renal replacement therapy

0.97 (0.64–1.47)

0.90

 ECMO

2.22 (1.08–4.59)

0.03

Use on the first day of hospitalization

 Antibiotics

0.36 (0.26–0.50)

< 0.001

 Vasoactive drug

1.91 (1.37–2.68)

< 0.001

  1. CI confidence interval, ECMO extracorporeal membrane oxygenation