From: Descriptive statistics and risk factor analysis of children with community-acquired septic shock
Variables | Hazard ratio (95% CI) | p |
---|---|---|
Age | ||
< 1 year | Reference | |
1–5 years | 1.90 (1.33–2.70) | < 0.001 |
6–19 years | 0.92 (0.62–1.36) | 0.679 |
Underlying conditions | ||
Care-dependence | 0.57 (0.41–0.80) | < 0.01 |
Neuromuscular | 1.29 (0.90–1.85) | 0.17 |
Cardiovascular | 0.89 (0.58–1.36) | 0.59 |
Hematological/malignancy/transplant | 0.67 (0.35–1.28) | 0.22 |
Congenital/genetic | 1.09 (0.55–2.7) | 0.81 |
Respiratory | 1.04 (0.47–2.28) | 0.92 |
Septic shock as admission diagnosis | 0.96 (0.72–1.27) | 0.76 |
Impaired consciousness | ||
Mild | Reference | |
Moderate | 0.98 (0.56–1.73) | 0.95 |
Severe | 1.49 (1.09–2.02) | 0.01 |
Transported from other hospitals | 0.71 (0.53–0.97) | 0.03 |
Admitted to accredited ICU | 0.52 (0.38–0.70) | < 0.001 |
Hospital volume | ||
1–2 | 1.94 (1.36–2.76) | < 0.001 |
3–6 | 1.26 (0.89–1.79) | 0.19 |
7–28 | Reference | |
Therapies within three days of hospitalization | ||
Mechanical ventilation | 3.26 (2.00–5.30) | < 0.001 |
Renal replacement therapy | 0.97 (0.64–1.47) | 0.90 |
ECMO | 2.22 (1.08–4.59) | 0.03 |
Use on the first day of hospitalization | ||
Antibiotics | 0.36 (0.26–0.50) | < 0.001 |
Vasoactive drug | 1.91 (1.37–2.68) | < 0.001 |