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Table 3 Results of the subgroup analyses by CPR in the weighted cohort

From: Effectiveness of systemic thrombolysis on clinical outcomes in high-risk pulmonary embolism patients with venoarterial extracorporeal membrane oxygenation: a nationwide inpatient database study

 

With CPR

   

Without CPR

  
 

Thrombolysis

Control

Risk differences

Thrombolysis

Control

Risk differences

Outcomes

(n = 263)

(n = 473)

(95% CI)

P-value

(n = 170)

(n = 314)

(95% CI)

P-value

Primary outcome

        

 In-hospital mortality, n (%)

172 (66)

309 (65)

0.3 (− 7.1 to 7.8)

0.93

67 (39)

150 (48)

− 8.5 (− 19.0 to 2.0)

0.11

Secondary outcomes

        

 Favorable neurological outcomes, n (%)

77 (29)

131 (28)

1.6 (− 5.5 to 8.7)

0.66

93 (55)

146 (47)

7.9 (− 2.5 to 18.4)

0.14

 Length of hospital stay, days, mean (SD)

24 (43)

21 (33)

2.4 (− 3.7 to 8.4)

0.45

33 (85)

27 (31)

6.3 (− 5.2 to 17.9)

0.28

 Length of VA-ECMO, days, mean (SD)

3 (3)

3 (4)

− 0.3 (− 0.8 to 0.3)

0.32

3 (3)

4 (4)

− 0.3 (− 1.0 to 0.4)

0.43

 Total hospitalization cost, × 103 dollars, mean (SD)

28 (23)

26 (21)

2.1 (− 1.5 to 5.7)

0.25

33 (29)

29 (21)

4.2 (− 1.2 to 9.5)

0.13

 Major bleeding in a critical area or organ, n (%)

11 (4)

10 (2)

2.0 (− 1.3 to 5.3)

0.24

12 (7)

11 (4)

3.6 (− 1.9 to 9.2)

0.20

 Intracranial bleeding, n (%)

4 (1)

3 (1)

0.9 (− 1.1 to 2.9)

0.37

6 (4)

6 (2)

1.9 (− 3.0 to 6.9)

0.45

 Blood transfusions, ml, mean (SD)

        

  Red blood cells

2710 (2450)

2628 (2882)

81 (− 373 to 536)

0.73

3144 (3172)

2649 (2682)

495 (− 158 to 1148)

0.14

  Fresh-frozen plasma

1361 (1611)

1463 (2161)

− 102 (− 420 to 216)

0.53

1831 (3280)

1329 (1776)

502 (− 180 to 1183)

0.15

  Platelet concentrate

236 (421)

271 (503)

− 35 (− 109 to 38)

0.34

327 (777)

337 (619)

− 9.4 (− 179 to 160)

0.91

  1. CI confidence interval, CPR cardiopulmonary resuscitation, SD standard deviation, VA-ECMO venoarterial extracorporeal membrane oxygenation