Table 1 Patient characteristics of the unweighted and weighted cohorts
Unweighted cohort | Weighted cohort | |||||
|---|---|---|---|---|---|---|
Thrombolysis | Control | Thrombolysis | Control | |||
(n = 432) | (n = 788) | ASD | (n = 433) | (n = 787) | ASD | |
Age, years, mean (SD) | 58 (16) | 60 (16) | 10 | 60 | 59 | 2 |
Men, n (%) | 179 (41) | 311 (39) | 4 | 40 | 40 | 1 |
Smoking history, n (%) | ||||||
Non-smoker | 270 (63) | 448 (57) | 12 | 60 | 59 | 1 |
Current or past smoker | 74 (17) | 121 (15) | 5 | 15 | 16 | 2 |
Unknown | 88 (20) | 219 (28) | 17 | 25 | 25 | 1 |
Body mass index on the day of admission, kg/m2, n (%) | ||||||
< 18.5 | 12 (3) | 37 (5) | 10 | 5 | 4 | 3 |
18.5–24.9 | 175 (41) | 300 (38) | 5 | 40 | 40 | 1 |
25.0–29.9 | 111 (26) | 193 (24) | 3 | 25 | 25 | 0 |
≥ 30.0 | 45 (10) | 72 (9) | 4 | 9 | 10 | 2 |
Missing | 89 (21) | 186 (24) | 7 | 22 | 22 | 1 |
Japan Coma Scale on the day of admission, n (%) | ||||||
0 (alert) | 127 (29) | 159 (20) | 22 | 23 | 23 | 1 |
1–3 (dizzy) | 50 (12) | 59 (7) | 14 | 9 | 9 | 0 |
10–30 (somnolent) | 21 (5) | 50 (6) | 7 | 6 | 6 | 3 |
100–300 (coma) | 234 (54) | 520 (66) | 24 | 62 | 62 | 1 |
Out-of-hospital cardiac arrest, n (%) | 206 (48) | 485 (62) | 28 | 57 | 57 | 1 |
Comorbidities, n (%) | ||||||
Coronary artery disease | 22 (5) | 48 (6) | 4 | 5 | 6 | 2 |
Heart failure | 59 (14) | 100 (13) | 3 | 13 | 13 | 0 |
Chronic lung disease | 8 (2) | 11 (1) | 4 | 2 | 1 | 0 |
Hypertension | 57 (13) | 91 (12) | 5 | 12 | 12 | 1 |
Diabetes mellitus | 30 (7) | 56 (7) | 1 | 8 | 7 | 2 |
Chronic kidney disease | 6 (1) | 12 (2) | 1 | 1 | 1 | 1 |
Cancer | 11 (3) | 45 (6) | 16 | 4 | 5 | 4 |
Ambulance use, n (%) | 385 (89) | 710 (90) | 3 | 90 | 90 | 1 |
Weekend admission, n (%) | 114 (26) | 176 (22) | 9 | 25 | 24 | 2 |
ICU admission, n (%) | 343 (79) | 614 (78) | 4 | 78 | 78 | 2 |
HCU admission, n (%) | 69 (16) | 146 (19) | 7 | 18 | 18 | 1 |
Procedures on the day of admission, n (%) | ||||||
Cardiopulmonary resuscitation | 268 (62) | 468 (59) | 5 | 61 | 60 | 1 |
Defibrillation | 36 (8) | 85 (11) | 8 | 10 | 10 | 2 |
Pacing | 17 (4) | 33 (4) | 1 | 4 | 4 | 1 |
TTM besides VA-ECMO | 78 (18) | 156 (20) | 4 | 20 | 19 | 2 |
Right heart catheterization | 59 (14) | 101 (13) | 3 | 13 | 13 | 1 |
Left heart catheterization | 58 (13) | 165 (21) | 20 | 18 | 18 | 0 |
Resuscitative drugs on the day of admission | ||||||
Adrenaline, mg, mean (SD) | 5 (5) | 5 (6) | 12 | 5 | 5 | 1 |
Vasopressin, n (%) | 27 (6) | 62 (8) | 6 | 8 | 8 | 4 |
Atropine, n (%) | 40 (9) | 60 (8) | 6 | 8 | 8 | 1 |
Amiodarone, n (%) | 18 (4) | 42 (5) | 6 | 5 | 5 | 2 |