Circulating and urinary microRNAs profile for predicting renal recovery from severe acute kidney injury

Table 3 Analysis of predictors to renal recovery

Characteristic	Univariate analysis		Multivariate analysis
Characteristic	Odds ratio (95% CI)	p-value	Odds ratio (95% CI)	p-value
miRNA 556-3p (cut-off 2.1)	2.89 (1.14–7.23)	0.03*	4.21 (1.28–13.84)	0.02*
DM	2.17 (0.89–5.31)	0.09
Age (per 5 year)	0.84 (0.72–0.98)	0.04*	0.95 (0.93–0.99)	0.02*
Creatinine on the first day of AKI stage 3	1.01 (0.89–1.15)	0.83
MAP	1.03 (1.00–1.06)	0.04*	1.04 (1.00–1.08)	0.05
Maximum non-renal SOFA score (per 2 point)	0.62 (0.45–0.84)	< 0.01*	0.77 (0.64–0.92)	< 0.01*
Hct	1.11 (1.02–1.21)	0.02*	1.09 (0.99–1.21)	0.09

miRNA microRNA, DM diabetes mellitus, MAP mean arterial pressure, SOFA Sequential Organ Failure Assessment, Hct hematocrit
*p-value < 0.05

ISSN: 2052-0492