Temporal trends of medical cost and cost-effectiveness in sepsis patients: a Japanese nationwide medical claims database

Table 2 Subgroup analyses for cost-effectiveness among sepsis patients

Subgroup	Coefficient ($)	95% CI	p-value
Age
Adults (20–64 years)	− 1635	− 2105 to − 1164	< 0.0001
Early elderly (65–74 years)	− 1892	− 2630 to − 1155	0.001
Late elderly (≥ 75 years)	− 1688	− 2397 to − 980	0.001
ICU
Yes	− 1784	− 2635 to − 933	0.002
No	− 1799	− 2512 to − 1086	< 0.0001
Transfer to other hospitals
Yes	− 1171	− 1866 to − 475	0.006
No	− 2001	− 2624 to − 1378	< 0.0001
Site of infection
Single	− 1628	− 2236 to − 1020	0.001
Multiple	− 2224	− 2866 to − 1582	< 0.0001
Mechanical ventilation
Yes	− 3182	− 4204 to − 2160	< 0.0001
No	− 1537	− 2206 to − 869	0.001
Vasopressor therapy
Yes	− 3381	− 4494 to − 2268	< 0.0001
No	− 1690	− 2352 to − 1028	0.001
Renal replacement therapy
Yes	− 3226	− 4010 to − 2441	< 0.0001
No	− 1661	− 2320 to − 1003	0.001

ISSN: 2052-0492