Extracorporeal cardiopulmonary resuscitation with temperature management could improve the neurological outcomes of out-of-hospital cardiac arrest: a retrospective analysis of a nationwide multicenter observational study in Japan

Table 4 Comparison of the proportions of patients with favorable neurological outcome (CPC 1–2) between ECPR with or without TTM using propensity score analysis with the IPTW method among cases with a cardiogenic cause

Variables	Treatment	n	CPC 1–2	OR (95% CI)	P value
All cases	ECPR with TTM ECPR without TTM	442 422	72 (16%) 41 (10%)	1.655 (1.096–2.500)	0.017
ICPS > 30 min	ECPR with TTM ECPR without TTM	419 401	67 (16%) 32 (8%)	1.966 (1.255–3.079)	0.003
ICPS > 45 min	ECPR with TTM ECPR without TTM	302 327	40 (13%) 18 (6%)	2.356 (1.312–4.233)	0.004
ICPS > 60 min	ECPR with TTM ECPR without TTM	117 168	13 (11%) 3 (2%)	4.544 (1.233–16.741)	0.024

P values < 0.05 were bolded
The propensity score analysis incorporated the following variables: age, sex, BCPR, SR, and ICPS
CPC Glasgow–Pittsburgh Cerebral Performance Category, OR odds ratio, CI confidence interval, ECPR extracorporeal cardiopulmonary resuscitation, BCPR bystander cardiopulmonary resuscitation, SR shockable rhythm, TTM target temperature management, ICPS interval from collapse to pump start, IPTW inverse probability of the treatment-weighting

ISSN: 2052-0492