Construction of a predictive model and prognosis of left ventricular systolic dysfunction in patients with sepsis based on the diagnosis using left ventricular global longitudinal strain

Table 3 Diagnostic performance of PCT, Hs-TnI, NT-proBNP, Lac and SOFA for left ventricular systolic dysfunction in patients with sepsis

Variable	AUC	Optimal cut-off value	Sensitivity (%)	Specificity (%)	95% CI		Yoden index	p
Variable	AUC	Optimal cut-off value	Sensitivity (%)	Specificity (%)	Upper limit	Lower limit	Yoden index	p
PCT	0.631	40	45.1	83.6	0.528	0.733	0.287	0.013
Hs-TnI	0.765	0.131	68.6	79.5	0.675	0.856	0.481	< 0.001
NT-proBNP	0.726	3270	58.8	78.1	0.637	0.815	0.369	< 0.001
Lac	0.641	4.2	47.1	84.9	0.540	0.741	0.320	0.006
SOFA	0.643	11	66.7	63.0	0.541	0.746	0.297	0.006
VDI	0.641	57	41.2	84.9	0.541	0.741	0.261	0.006

PCT rocalcitonin, Hs-TnI high sensitive troponin I, NT-proBNP N-terminal pro-brain natriuretic peptide, Lac lactate, SOFA Sequential Organ Failure Assessment, VDI vasopressor dosing intensity = [norepinephrine (ug/min)] + [dopamine (ug/kg/min) /2] + [epinephrine (ug/min)] + [phenylephrine (ug/min) /10] + [vasopressin (0.01 units/min) × 2]. AUC area under the curve, 95%CI 95% confidence interval

ISSN: 2052-0492