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Table 2 Multi-variable Cox regression analysis results for predicting in-hospital mortality

From: Worsening or improving hypoalbuminemia during continuous renal replacement therapy is predictive of patient outcome: a single-center retrospective study

 

HR (95% CI)

p-value

Model I

 Albumin changing pattern

  Persistent low

Reference

 

  Increasing

0.571 (0.340, 0.958)

0.034

  Decreasing

0.722 (0.455, 1.146)

0.167

  Persistent high

0.565 (0.353, 0.903)

0.017

 Age, year

1.014 (1.002, 1.027)

0.023

 SOFA score

1.089 (1.036, 1.455)

< 0.001

Model II

 Serum albumin at Day 3, g/dL

0.532 (0.377, 0.751)

< 0.001

 Age, year

1.017 (1.006, 1.029)

0.004

 COPD

1.887 (1.104, 3.226)

0.020

 SOFA score

1.088 (1.042, 1.137)

< 0.001

  1. Final model: adjusted with age, BMI, COPD, CKD, sepsis, SOFA score and CRRT delivered dose
  2. SOFA Sequential Organ Failure Assessment, BMI body mass index, COPD chronic obstructive pulmonary disease, CKD chronic kidney disease, CRRT continuous renal replacement therapy