Soluble mannose receptor CD206 and von Willebrand factor are early biomarkers to identify patients at risk for severe or necrotizing acute pancreatitis

Table 3 Binary logistic regression analysis to identify patients with severe/necrotizing pancreatitis

Characteristics	Univariate analysis		Adjusted for etiology^#		Adjusted for etiology^# and age
Characteristics	Univariate odds ratio (95% CI)	P value	Adjusted odds ratio (95% CI)	P value	Adjusted odds ratio (95% CI)	P value
sCD206*
Prospective cohort ICU cohort	6.08 (1.77–20.81) 2.90 (1.19–7.05)	0.004 0.02	4.29 (1.20–15.37) 2.95 (1.21–7.22)	0.03 0.02	5.96 (1.46–24.30) 3.33 (1.22–9.13)	0.01 0.02
sCD206 Q4^$
Prospective cohort ICU cohort	9.18 (2.54–33.23) 4.38 (1.08–17.71)	0.001 0.04	8.69 (1.90–39.70) 4.45 (1.09–18.11)	0.005 0.04	17.54 (2.63–117.1) 8.31 (1.66–41.68)	0.003 0.01
vWF:Ag*
Prospective cohort ICU cohort	9.33 (1.05–82.81) 3.34 (1.04–10.67)	0.04 0.04	102.0 (2.1–5016.8) 3.69 (1.11–12.27)	0.02 0.03	205.0 (2–2–18,729.5) 8.40 (1.61–43.92)	0.02 0.01
vWF:Ag Q4^$
Prospective cohort ICU cohort	5.25 (1.19–23.17) 4.00 (0.77–20.92)	0.03 0.10	9.45 (0.90–98.92) 4.02 (0.74–21.71)	0.06 0.11	12.43 (0.96–161.76) 8.69 (1.18–64.13)	0.05 0.03

*log_e-transformed values were used. ^#stratified by biliary vs. alcoholic vs. other etiologies. ^$The fourth quartile in each cohort was compared to the other quartiles (Q1–Q3) within the cohort

ISSN: 2052-0492