Table 1 Clinical characteristics of patients with acute pancreatitis (Prospective cohort)

Age (years)

48 (41; 59)

69 (52; 78)

0.001

Male sex

10 (71%)

39 (58%)

0.55

Body weight (kg)

78 (67.25; 101.25)

83 (71; 92)

0.97

BMI (kg/m²)

28.2 (23.5; 31.1)

27.7 (25.0; 31.0)

0.64

Etiology

 Biliary

 Alcoholic

 Other

2 (14%)

8 (57%)

4 (29%)

31 (46%)

5 (7%)

31 (46%)

0.001

Alcohol use (n)

12 (86%)

23 (34%)

0.001

Smoker (n)

5 (36%)

12 (15%)

0.16

Hemoglobin (mmol/l)

9.0 (7.9; 10.4)

8.2 (7.5; 9.3)

0.18

6.7 (6.4; 7.7)

7.6 (6.9; 8.1)

0.05

Hematocrit (%)

39 (36; 48)

40 (36; 44)

0.92

32 (30; 37)

37 (33; 38)

0.04

INR

1.0 (1.0; 1.4)

1.1 (1.1; 1.3)

0.39

1.2 (1.1; 1.5)

1.2 (1.1; 1.3)

0.68

PTT (sec)

26.8 (24.3; 30.2)

27.6 (35.4; 30.0)

0.36

27.6 (26.0; 29.4)

28.3 (26.9; 30.9)

0.23

Platelets (/nl)

195 (166; 347)

254 (183; 297)

0.61

148 (116; 213)

203 (155; 259)

0.07

Ca²⁺ (mmol/l)

2.21 (1.93; 2.49)

2.39 (2.21; 2.73)

0.07

1.98 (1.70; 2.10)

2.23 (2.15; 2.30)

 < 0.001

Ca²⁺ corrected (mmol/l)

2.48 (2.27; 2.68)

2.49 (2.36; 2.60)

1.00

2.50 (2.26; 2.53)

2.49 (2.39; 2.61)

0.52

LDH (µmol/l/s)

4.33 (3.32; 4.74)

4.31 (3.36; 6.22)

0.75

5.45 (4.97; 14.83)

4.02 (3.31; 5.14)

0.002

Bilirubin (µmol/l)

16.5 (9.75; 34.75)

32 (14; 56.25)

0.11

14 (10.25; 22)

18 (12; 31.5)

0.32

ALP (µmol/l/s)

1.33 (1.15; 2.22)

2.04 (1.32; 3.72)

0.06

1.48 (1.00; 2.27)

1.54 (1.06; 3.06)

0.44

GGT (µmol/l/s)

3.10 (1.14; 4.49)

4.99 (1.05; 8.75)

0.46

2.00 (0.80; 6.16)

2.83 (0.86; 7.38)

0.55

Amylase (µmol/l/s)

7.45 (6.17; 18.54)

13.74 (3.96; 28.40)

0.52

6.5 (2.41; 11.53)

1.70 (0.86; 3.20)

0.02

Lipase (µmol/l/s)

31.64 (9.85; 53.45)

43.08 (9.84; 97.75)

0.38

5.60 (3.03; 11.07)

2.06 (1.07; 4.85)

0.004

ALT (µmol/l/s)

0.49 (0.27; 0.88)

1.64 (0.43; 4.40)

0.06

0.29 (0.19; 0.87)

1.10 (0.29; 2.62)

0.03

AST (µmol/l/s)

0.88 (0.48; 1.70)

1.52 (0.53; 3.58)

0.20

0.89 (0.72; 1.48)

0.67 (0.43; 1.19)

0.15

Albumin (g/l)

29 (26; 38)

34 (31; 38)

0.15

21 (17; 24)

29 (26; 32)

 < 0.001

pH

7.40 (7.36; 7.44)

7.41 (7.38; 7.44)

0.46

7.39 (7.33; 7.43)

7.40 (7.38; 7.43)

0.38

Lactate (mmol/l)

1.47 (1.03; 2.10)

1.40 (1.05; 2.09)

0.89

0.85 (0.70; 1.10)

1.01 (0.78; 1.25)

0.32

Glucose (mmol/l)

8.4 (5.7; 10.2)

7.0 (5.8; 8.8)

0.26

7.9 (4.4; 9.4)

5.9 (5.1; 7.2)

0.25

Urea (mmol/l)

6.6 (5.9; 10.5)

6.0 (4.2; 8.1)

0.40

6.5 (4.4; 12.0)

4.6 (3.1; 6.8)

0.04

Creatinine (µmol/l)

79 (69.5; 157.5)

77 (68; 102.5)

0.37

85.5 (55.5; 135.75)

69 (61; 88.25)

0.34

Standard bicarbonate (mmol/l)

23.6 (21.5; 26.1)

24.6 (23.1; 26.3)

0.37

21.3 (19.1; 27.4)

25.2 (23.8; 26.7)

0.08

Base Excess (mmol/l)

0.3 (-4.8; 1.4)

0.9 (-1.3; 2.9)

0.13

-2.5 (-6.5; 3.7)

1.1 (-0.4; 2.6)

0.11

SOFA score

1.0 (0.5; 2.5)

2 (0; 2.25)

0.95

1.0 (1.0; 3.75)

1.0 (0; 2)

0.10

BISAP score

1 (0; 1,75)

1 (1; 2)

0.53

N/A

SAPS II score

17 (13; 24)

22 (16; 26)

0.11

18 (11.5; 30.5)

20 (7; 25)

0.75

APACHE II score

7 (5.75; 8.75)

8 (5; 13)

0.27

N/A

CCI (points)

1.5 (0; 2)

3 (1; 6)

0.008

N/A

Ranson Criteria

N/A

2.5 (0.25; 3.75)

1 (0; 2)

0.10

SIRS (points)

1.5 (0.5; 2)

0.5 (0; 1)

0.005

N/A

CRP (mg/l)

82.5 (8.7; 222.2)

24.9 (3.8; 70.9)

0.12

367 (306; 400)

127 (35; 215)

 < 0.001

PCT (ng/ml)

0.48 (0.93; 2.80)

0.22 (0.07; 0.51)

0.49

1.81 (0.34; 7.34)

0.19 (0.11; 0.73)

0.002

WBC (/nl)

14.6 (9.1; 18.3)

11.9 (9.0; 15.9)

0.16

12.3 (8.3, 17.5)

9.7 (7.1; 11.6)

0.046

sCD206 (mg/l)

1.57 (0.59; 1.89)

0.66 (0.51; 0.95)

0.005

2.41 (1.31–2.58)

0.86 (0.59; 1.23)

 < 0.001

Fibrinogen (g/l)

3.2 (2.7; 4.7)

3.8 (3.2; 4.7)

0.50

8.3 (3.9; 10.0)

5.0 (3.8; 6.2)

0.06

D-Dimer (µg/l)

896 (312; 1948)

468 (310; 864)

0.26

2833 (1578; 4531)

646 (355; 1169)

 < 0.001

vWF:Ag (%)

375 (285; 401)

257 (204; 355)

0.02

393 (288; 580)

235 (198; 342)

0.001

vWF:RCo (%)

401 (302; 433)

266 (194; 339)

0.01

428 (319; 646)

255 (200; 352)

 < 0.001