Skip to main content

Table 2 Ventilator settings, physiological data, and blood gas analysis in each section

From: Accuracy evaluation of mainstream and sidestream end-tidal carbon dioxide monitoring during noninvasive ventilation: a randomized crossover trial (MASCAT-NIV trial)

  During SBT Noninvasive ventilation P value*
Previous method Novel method
Ventilation mode     1.000
 PSV, n (%) NA 50 (83.3) 51 (85.0)  
 CPAP, n (%) NA 10 (16.7) 9 (15.0)  
FIO2, median (IQR) 0.3 (0.3–0.4) 0.3 (0.3–0.4) 0.3 (0.3–0.4) 1.000
PEEP, median (IQR), cmH2O 5 (5–5) 4 (4–4) 4 (4–4) 1.000
PS, median (IQR), cmH2O† 5 (5–5) 4 (2–4) 4 (2–4) 1.000
Heart rate, mean (SD), bpm 85.0 (15.5) 85.0 (14.7) 85.5 (15.1) 0.351
Mean blood pressure, mean (SD), mmHg 81.2 (11.6) 82.1 (11.6) 80.5 (11.6) 0.063
Respiratory Rate, mean (SD), breaths /min 15.9 (4.9) 18.2 (5.8) 19.1 (6.1) 0.108
Tidal Volume, mean (SD), mL 528 (157) 469 (130) 474 (122) 0.692
Minute ventilation, mean (SD), L/min 7.9 (2.3) 8.1 (3.2) 8.6 (3.3) 0.084
RSBI, mean (SD) 33.6 (16.1) 43.1 (20.4) 42.9 (17.0) 0.939
Total leakage, mean (SD), L/min NA 45.1 (11.5) 36.1 (8.3)  < 0.001
PaO2, median (IQR), mmHg 87.3 (77.5–100.0) 86.2 (76.0–100.5) 89.6 (75.9–97.9) 0.793
P/F ratio, median (IQR) 290 (214–364) 271 (216–335) 280 (211–342) 0.601
PaCO2, mean (SD), mmHg 37.6 (5.7) 38.2 (5.5) 38.4 (5.4) 0.286
PETCO2, mean (SD), mmHg 35.1 (5.8) 32.0 (6.3) 35.7 (5.5)  < 0.001
pH, mean (SD) 7.43 (0.05) 7.42 (0.05) 7.42 (0.05) 0.610
  1. CPAP, continuous positive airway pressure; FIO2, fraction of inspiratory oxygen; NA, not applicable; PaCO2, arterial partial pressure of carbon dioxide; PaO2, arterial partial pressure of oxygen; PEEP, positive end expiratory pressure; PETCO2, end-tidal partial pressure of carbon dioxide; P/F ratio, ratio of arterial oxygen partial pressure to fractional inspired oxygen; PS, pressure support; PSV, pressure support ventilation; RSBI, rapid shallow breathing index; SBT, spontaneous breathing trial
  2. *Compared measurements in patients using the novel method with the previous method
  3. Among patients who underwent PSV during noninvasive ventilation