Association between the presence of delirium during intensive care unit admission and cognitive impairment or psychiatric problems: the Korean ICU National Data Study

Table 2 Hazard ratio (95% CI) for cognitive impairment and psychiatric problems within 2 years of discharge in patients with delirium versus patients without delirium

	Delirium		Non-delirium		Univariable		Multivariable^a
	Number of cases	Incidence rate, (1000 person-years)	Number of cases	Incidence rate, (1000 person-years)	HR (95% CI)	p	HR (95% CI)	p
Overall (n = 306,011)
Cognitive impairment	27,462	210.8	20,017	156.2	1.25 (1.07–1.48)	0.006	1.17 (1.05–1.29)	0.004
Psychiatric problems	37,574	293.4	20,736	153.4	1.80 (1.67–1.94)	< 0.001	1.78 (1.67–1.90)	< 0.001
Readmission to hospital	107,207	695.7	81,300	539.4	1.22 (1.20–1.24)	< 0.001	1.24 (1.21–1.26)	< 0.001
Readmission to ICU	23,685	86.6	16,891	71.5	1.16 (1.14–1.19)	< 0.001	1.12 (1.10–1.14)	< 0.001
Patients who needed advanced interventions (n = 137,833)
Cognitive impairment	14,813	197.0	5592	179.7	1.08 (0.83–1.40)	0.59	1.08 (0.91–1.29)	0.39
Psychiatric problems	20,983	286.3	5414	161.3	1.70 (1.59–1.82)	< 0.001	1.63 (1.55–1.72)	< 0.001
Readmission to hospital	64,056	735.3	23,370	624.5	1.15 (1.09–1.21)	< 0.001	1.07 (1.03–1.10)	< 0.001
Readmission to ICU	14,909	94.5	5012	80.5	1.17 (1.09–1.24)	< 0.001	1.03 (0.98–1.09)	0.23

CI confidence interval, HR hazard ratio, ICU intensive care unit
^aAdjusted for age, sex, comorbidities, medical beneficiaries, region, mechanical ventilation, ECMO, hemodialysis, vasopressor drugs, quality of ICU, and ICU length of stay more than 7 days

ISSN: 2052-0492