| World (not including Japan) | Japan | p value |
---|---|---|---|
Q-1. Criteria used for UFNET initiation, N (%) | |||
(a) Persistent oliguria/anuria (urine output < 0.5 mL/kg/h for ≥ 12 h) | 477 (50.9) | 38 (26.6) | < 0.001 |
(b) Severe hypoxemia (PaO2/FIO2 ratio < 150) | 134 (14.3) | 18 (12.6) | 0.586 |
(c) Pulmonary edema with or without hypoxemia | 162 (17.3) | 32 (22.4) | 0.138 |
(d) Cumulative fluid balance (> 1000 mL) | 51 (5.4) | 3 (2.1) | 0.088 |
(e) Fluid overload > 10% of body weight | 57 (6.1) | 3 (2.1) | 0.053 |
(f) Ongoing need for fluids in the presence of oliguria | 57 (6.1) | 49 (34.3) |  < 0.001 |
Total | 938 | 143 | Â |
Q-2. Criteria used for UFNET prescription, N (%) | |||
(a) 24-h fluid balance | 148 (14.8) | 8 (5.3) | 0.001 |
(b) Cumulative fluid balance | 201 (20.1) | 29 (19.1) | 0.765 |
(c) Weight gain | 48 (4.8) | 21 (13.8) | < 0.001 |
(d) Radiographic features of fluid overload | 21 (2.1) | 10 (6.6) | 0.002 |
(e) Hemodynamic status (HR, BP, CVP, PPV, dose of vasopressors) | 552 (55.3) | 82 (53.9) | 0.763 |
(f) Volume of anticipated fluid use in the next 24Â h | 22 (2.2) | 1 (0.7) | 0.205 |
(g) Arterial lactate | 7 (0.7) | 1 (0.7) | 0.953 |
Total | 999 | 152 | Â |
Q-3. Method used to achieve UFNET using CRRT, N (%) | |||
(a) By varying ultrafiltration rate only | 536 (48.6) | 77 (54.2) | 0.203 |
(b) By varying replacement fluid rate only | 60 (5.4) | 20 (14.1) | < 0.001 |
(c) By varying both ultrafiltration and replacement fluid rate | 508 (46.0) | 45 (31.7) | 0.001 |
Total | 1104 | 142 | Â |
Q-4. How frequently did you check net fluid balance during CRRT? N (%) | |||
(a) ≤ Every 1 h | 409 (35.8) | 32 (21.9) | < 0.001 |
(b) ≤ Every 2 h | 511 (44.8) | 60 (41.1) | 0.398 |
(c) ≤ Every 4 h | 660 (57.8) | 89 (61.0) | 0.473 |
(d) ≤ Every 6 h | 772 (67.7) | 104 (71.2) | 0.383 |
(e) ≤ Every 8 h | 884 (77.5) | 127 (87.0) | 0.009 |
(f) ≤ Every 12 h | 1015 (89.0) | 136 (93.2) | 0.121 |
(g) ≤ Every 24 h | 1141 (100) | 146 (100) | na |