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Table 1 Comparison of hemodynamic data before and after esmolol administration in patients with septic shock

From: Esmolol response in septic shock patients in relation to vascular waterfall phenomenon measured by critical closure pressure and mean systemic filling pressure: a prospective observational study

Variables Before treatment After treatment P
Mean SD Mean SD
CI (L/min/m2) 4.0 0.5 3.3 0.5 0.000
SI (mL/m2) 34.1 4.9 36.6 5.6 0.008
HR (beats/min) 116.8 10.1 90.6 4.8 0.000
MAP (mmHg) 71.4 3.1 72.0 1.9 0.309
CVP (mmHg) 12.4 1.5 12.8 1.7 0.273
GEDVI (mL/m2) 748.0 25.7 751.9 25.8 0.426
ITBVI (mL/m2) 906.1 47.0 903.0 41.6 0.676
EVLWI (mL/kg) 13.3 4.7 13.4 3.9 0.888
Pcc (mmHg) 31.4 10.9 36.7 9.4 0.008
Pmsf (mmHg) 27.7 4.7 26.7 4.5 0.293
Slope of VO curve (L/min/mmHg) 0.109 0.040 0.104 0.044 0.511
Slope of VR curve (L/min/mmHg) -0.294 0.136 -0.290 0.210 0.906
Pcc-Pmsf (mmHg) 4.0 12.1 10.0 10.0 0.009
Pmsf-CVP (mmHg) 15.3 4.8 13.9 5.0 0.179
RIs (mmHg·min·m2/L) 15.14 2.02 18.25 2.79 0.000
RIa (mmHg·min·m2/L1) 10.14 2.98 10.80 3.04 0.264
RIv (mmHg·min·m2·L−1) 3.91 1.30 4.25 1.57 0.231
RIa + RIv (mmHg·min·m2/L1) 14.05 3.51 15.05 3.40 0.145
Norepinephrine dosage (μg/kg/min) 0.20 0.05 0.20 0.04 0.444
Urine output per hour (mL/kg/h) 1.40 0.49 1.45 0.54 0.589