Non-invasive detection of a femoral-to-radial arterial pressure gradient in intensive care patients with vasoactive agents

Table 2 Diagnostic accuracy of non-invasive brachial-to-radial (NIBR-APG) arterial pressure gradient to detect a significant invasive mean and systolic femoral-to-radial arterial pressure gradient (FR-APG)

	Approaches	AUC–ROC [95%CI]	Best threshold (mm Hg)	Specificity	Sensitivity	PPV	NPV	Accuracy
MAP FR-APG (∆MAP > 10 mm Hg)	NIBR-APG avg (n = 66) (3 measurements)	0.93 [0.81–0.99]	11 [3; 16]	92 [67; 100]	100 [83;100]	50 [21; 100]	100 [97; 100]	91 [65; 99]
	NIBR-APG initial (n = 81) (1 measurement)	0.83 [0.61–0.95]	5 [-6; 11]	78 [62–97]	80 [60–100]	36 [23–75]	97 [94–100]	79 [64–95]
SAP FR-APG (∆SAP > 25 mm Hg)	NIBR-APG avg (n = 66) (3 measurements)	0.85 [0.71–0.97]	18 [-2; 27]	84 [53; 98]	88 [63; 100]	40 [20–83]	97 [94.100]	84 [53; 96]
	NIBR-APG initial (n = 81) (1 measurement)	0.80 [0.61–0.95]	14 [3; 25]	86 [66; 97]	75 [50; 100]	50 [28; 82]	95 [91; 98]	86 [70; 95]

AUC-ROC area under the curve of the receiver operating characteristic; NPV negative predictive value; PPV positive predictive value; NIBR-APG avg non-invasive brachial to radial arterial pressure gradient averaged from T1 to T3, considering the mean arterial pressure, at the radial level with a catheter and non-invasively on both arms with a cuff at the brachial level; FR-APG femoral-radio arterial pressure gradient, considering the mean arterial pressure, at the radial level with a catheter and with a femoral catheter to assess central arterial pressure; NIBR-APG initial non-invasive brachial to radial arterial pressure gradient at T1, considering the mean arterial pressure, at the radial level with a catheter and non-invasively on both arms with a cuff at the brachial level; MAP mean arterial pressure; SAP systolic arterial pressure gradient

ISSN: 2052-0492