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Table 2 Diagnostic accuracy of non-invasive brachial-to-radial (NIBR-APG) arterial pressure gradient to detect a significant invasive mean and systolic femoral-to-radial arterial pressure gradient (FR-APG)

From: Non-invasive detection of a femoral-to-radial arterial pressure gradient in intensive care patients with vasoactive agents

  Approaches AUC–ROC [95%CI] Best threshold
(mm Hg)
Specificity Sensitivity PPV NPV Accuracy
MAP FR-APG (∆MAP > 10 mm Hg) NIBR-APG avg
(n = 66)
(3 measurements)
0.93 [0.81–0.99] 11 [3; 16] 92 [67; 100] 100 [83;100] 50 [21; 100] 100 [97; 100] 91 [65; 99]
  NIBR-APG initial
(n = 81)
(1 measurement)
0.83 [0.61–0.95] 5 [-6; 11] 78 [62–97] 80 [60–100] 36 [23–75] 97 [94–100] 79 [64–95]
SAP FR-APG
(∆SAP > 25 mm Hg)
NIBR-APG avg
(n = 66)
(3 measurements)
0.85 [0.71–0.97] 18 [-2; 27] 84 [53; 98] 88 [63; 100] 40 [20–83] 97 [94.100] 84 [53; 96]
  NIBR-APG initial
(n = 81)
(1 measurement)
0.80 [0.61–0.95] 14 [3; 25] 86 [66; 97] 75 [50; 100] 50 [28; 82] 95 [91; 98] 86 [70; 95]
  1. AUC-ROC area under the curve of the receiver operating characteristic; NPV negative predictive value; PPV positive predictive value; NIBR-APG avg non-invasive brachial to radial arterial pressure gradient averaged from T1 to T3, considering the mean arterial pressure, at the radial level with a catheter and non-invasively on both arms with a cuff at the brachial level; FR-APG femoral-radio arterial pressure gradient, considering the mean arterial pressure, at the radial level with a catheter and with a femoral catheter to assess central arterial pressure; NIBR-APG initial non-invasive brachial to radial arterial pressure gradient at T1, considering the mean arterial pressure, at the radial level with a catheter and non-invasively on both arms with a cuff at the brachial level; MAP mean arterial pressure; SAP systolic arterial pressure gradient