Period of time | ICU patients’ spouses (n = 7248) | Matched individuals (n = 29,423) | Adjusted odds ratio (95% CI) * | P value |
---|---|---|---|---|
Anxiolytics and hypnotics/sedatives | ||||
Overall (prescribed within 6 months) | 323 (4.5) | 1,143 (3.9) | 1.16 (1.01–1.32) | 0.03 |
Index date to 1 month | 79 (1.1) | 247 (0.8) | 1.33 (1.01–1.75) | 0.04 |
1–2 months | 107 (1.5) | 310 (1.1) | 1.40 (1.11–1.77) | 0.004 |
2–3 months | 106 (1.5) | 366 (1.2) | 1.15 (0.92–1.45) | 0.20 |
3–4 months | 102 (1.4) | 375 (1.3) | 1.13 (0.90–1.41) | 0.30 |
4–5 months | 107 (1.5) | 360 (1.2) | 1.25 (1.00–1.57) | 0.05 |
5–6 months | 105 (1.4) | 368 (1.3) | 1.25 (1.00–1.57) | 0.05 |
Antidepressants | ||||
Overall (prescribed within 6 months) | 27 (0.4) | 79 (0.3) | 1.39 (0.88–2.18) | 0.15 |
Index date to 1 month | 4 (0.1) | 24 (0.1) | 0.66 (0.22–1.92) | 0.44 |
1–2 months | 14 (0.2) | 33 (0.2) | 1.62 (0.86–3.07) | 0.14 |
2–3 months | 14 (0.2) | 38 (0.2) | 1.34 (0.72–2.50) | 0.36 |
3–4 months | 14 (0.2) | 47 (0.2) | 1.08 (0.59–1.99) | 0.80 |
4–5 months | 12 (0.2) | 46 (0.2) | 1.01 (0.52–1.95) | 0.98 |
5–6 months | 14 (0.2) | 46 (0.2) | 1.30 (0.70–2.41) | 0.40 |