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Table 3 Proportions of ICU patients’ spouses and matched individuals who were prescribed anxiolytics, hypnotics/sedatives, or antidepressants

From: Association between intensive care unit admission of a patient and mental disorders in the spouse: a retrospective matched-pair cohort study

Period of time

ICU patients’ spouses (n = 8490)

Matched individuals

(n = 33,946)

Adjusted odds ratio (95% CI) *

P value

Anxiolytics and hypnotics/sedatives

    

Overall (prescribed within 6 months)

1081 (12.7)

3619 (10.7)

1.19 (1.07–1.32)

0.001

 Index date to 1 month

724 (8.5)

2288 (6.7)

1.32 (1.13–1.54)

 < 0.001

 1–2 months

680 (8.0)

2226 (6.6)

1.29 (1.12–1.49)

0.001

 2–3 months

602 (7.1)

2218 (6.5)

1.03 (0.90–1.19)

0.645

 3–4 months

614 (7.2)

2132 (6.3)

1.01 (0.88–1.17)

0.85

 4–5 months

565 (6.7)

2211 (6.0)

1.08 (0.93–1.25)

0.32

 5–6 months

548 (6.5)

2024 (6.0)

1.02 (0.88–1.18)

0.78

Antidepressants

    

Overall (prescribed within 6 months)

233 (2.7)

838 (2.5)

1.15 (0.85–1.56)

0.37

 Index date to 1 month

190 (2.2)

700 (2.1)

0.96 (0.61–1.52)

0.86

 1–2 months

181 (2.1)

682 (2.0)

1.22 (0.82–1.83)

0.31

 2–3 months

167 (2.0)

666 (2.0)

1.14 (0.78–1.68)

0.50

 3–4 months

153 (1.8)

650 (1.9)

0.90 (0.61–1.33)

0.60

 4–5 months

148 (1.7)

620 (1.8)

0.95 (0.64–1.40)

0.79

 5–6 months

143 (1.7)

606 (1.8)

0.97 (0.65–1.43)

0.87

  1. Data are presented as n (%)
  2. ICU intensive care unit; CI confidence interval
  3. *Adjusted for age, sex, status of medical insurance, history of sleep disorders, history of anxiety disorders, history of mood disorders, history of post-traumatic stress disorders, and Charlson comorbidity index score