Table 4 Relationship between glucose variability and mortality
Unadjusted model | Adjusted model | Adjusted model with interaction | ||||
|---|---|---|---|---|---|---|
OR (95% CIs) | p value | OR (95% CIs) | p value | OR (95% CIs) | p value | |
Age | – | – | 1.02 [1.01, 1.03] | < 0.001*** | 1.05 [1.02, 1.08] | < 0.001*** |
Sex (female) | – | – | 0.76 [0.55, 1.03] | 0.079 | 0.75 [0.55, 1.03] | 0.072 |
Cholesterol | – | – | 0.95 [0.86, 1.06] | 0.359 | 0.95 [0.86, 1.06] | 0.357 |
APACHE II score | – | – | 1.10 [1.08, 1.12] | < 0.001*** | 1.10 [1.08, 1.12] | < 0.001*** |
Diabetes mellitus | – | – | 0.70 [0.50, 1.001] | 0.051 | 0.71 [0.50, 1.01] | 0.058 |
Mean glucose level | – | – | 1.00 [0.92, 1.10] | 0.944 | 1.00 [0.92, 1.10] | 0.925 |
Use of corticosteroids | – | – | 3.66 [2.68, 5.00] | < 0.001*** | 3.67 [2.68, 5.01] | < 0.001*** |
Glucose variability | 1.15 [1.03, 1.29] | 0.011* | 1.23 [1.06, 1.42] | 0.005** | 2.60 [1.33, 5.07] | 0.005** |
Glucose variability × age interaction | – | – | – | – | 0.99 [0.98, 0.999] | 0.025* |