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Table 3 Penalized logistic regression cross validation of predictive models

From: Cerebral autoregulation in anoxic brain injury patients treated with targeted temperature management

  Mortality Unfavourable outcome
OR (CI) p value OR (CI) p value
Age 1.04 (0.96–1.12) 0.347 1.02 (0.95–1.11) 0.550
Arterial hypertension 3.73 (0.69–20.16) 0.126 3.03 (0.63–14.64) 0.68
Shockable rhythm 0.15 (0.03–0.82) 0.029 0.44 (0.09–2.15) 0.312
Time to ROSC 1.01 (0.92–1.09) 0.909 1.01 (0.93–1.10) 0.809
Cardio-active medications 2.54 (0.47–13.75) 0.279 1.80 (0.37–8.74) 0.463
pCO2 (mmHg) 0.86 (0.72–1.02) 0.088 0.87 (0.73–1.05) 0.156
EEG HMp 16.42 (2.06–130.96) 0.008 10.01 (1.23–81.34) 0.031
Mxa 1.04 (1.01–1.07) 0.011 1.03 (1.01–1.06) 0.049
  1. The fitted models showed an accuracy of 84% (CI 71–93%), a sensitivity of 68% and a specificity of 94% for mortality, and an accuracy of 86% (CI 73–94%), a sensitivity of 100% and a specificity of 50% for unfavourable outcome. CI confidence interval, EEG HMp highly malignant electroencephalography during ICU stay, Mxa mean flow index during normothermia, OR odds ratio, pCO2 arterial carbon dioxide partial pressure during normothermia, ROSC return of spontaneous circulation. Cardio-active medications: noradrenaline (norepinephrine) and/or dobutamine