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Table 2 Laboratory and shock treatment characteristics

From: Clinical significance of lactate clearance in patients with cardiogenic shock: results from the RESCUE registry

  High lactate clearance Low lactate clearance p value
n = 333 n = 295
Laboratory findings, Initial
 Hemoglobin (mg/dL) 12.7 (10.5–14.7) 12.2 (10.5–14.0) 0.039
 Serum glucose (mg/dL) 222.0 (150.0–319.0) 183.0 (134.0–269.0) 0.001
 Total bilirubin (mg/dL) 0.6 (0.4–1.2) 0.7 (0.5–1.2) 0.021
 Creatinine (mg/dL) 1.3 (1.0–1.7) 1.2 (0.9–1.8) 0.085
 Lactate (mmol/L, at admission) 6.9 (4.7–1.0) 3.7 (2.3–7.1)  < 0.001
 Lactate (mmol/L, 24 h after admission) 1.2 (0.9–1.7) 2.3 (1.4–6.8)  < 0.001
 Lactate clearance (%) 80.0 (72.1–86.5) 36.2 (0.0–53.6)  < 0.001
 NT–proBNP (pg/mL) 5884.5 (1015.5–21,827.8) 5152.0 (1506.5–13,628.5) 0.424
Vasoactive inotropic score 27.7 (8.0–80.0) 37.0 (10.0–110.0) 0.006
Use of venous central line 218 (65.5) 200 (67.8) 0.537
Use of mechanical circulatory support 0.134
 None 138 (41.4) 97 (32.9)  
 ECMO 126 (37.8) 127 (43.1)  
 IABP 51 (15.3) 48 (16.3)  
 ECMO + IABP 18 (5.4) 23 (7.8)  
Shock-to-ECMO time < 24 h 126 (37.8) 133 (45.1) 0.066
ECPR 62 (18.6) 72 (24.4) 0.077
Continuous renal replacement therapy 75 (22.5) 109 (36.9)  < 0.001
Mechanical ventilation 219 (65.8) 198 (67.1) 0.720
Length of intensive care unit stay (day) 8.0 (4.0–16.5) 6.0 (2.0–15.0) 0.002
Length of hospital stay (day) 14.0 (8.0–28.0) 11.0 (5.0–27.0) 0.001
  1. Values are shown as n (%) or median (interquartile range)
  2. ECMO extracorporeal membrane oxygenation, ECPR extracorporeal cardiopulmonary resuscitation, IABP intra-aortic balloon pump, Nt-proBNP N-terminal pro B-type natriuretic peptide