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Table 2 Laboratory and shock treatment characteristics

From: Clinical significance of lactate clearance in patients with cardiogenic shock: results from the RESCUE registry

 

High lactate clearance

Low lactate clearance

p value

n = 333

n = 295

Laboratory findings, Initial

 Hemoglobin (mg/dL)

12.7 (10.5–14.7)

12.2 (10.5–14.0)

0.039

 Serum glucose (mg/dL)

222.0 (150.0–319.0)

183.0 (134.0–269.0)

0.001

 Total bilirubin (mg/dL)

0.6 (0.4–1.2)

0.7 (0.5–1.2)

0.021

 Creatinine (mg/dL)

1.3 (1.0–1.7)

1.2 (0.9–1.8)

0.085

 Lactate (mmol/L, at admission)

6.9 (4.7–1.0)

3.7 (2.3–7.1)

 < 0.001

 Lactate (mmol/L, 24 h after admission)

1.2 (0.9–1.7)

2.3 (1.4–6.8)

 < 0.001

 Lactate clearance (%)

80.0 (72.1–86.5)

36.2 (0.0–53.6)

 < 0.001

 NT–proBNP (pg/mL)

5884.5 (1015.5–21,827.8)

5152.0 (1506.5–13,628.5)

0.424

Vasoactive inotropic score

27.7 (8.0–80.0)

37.0 (10.0–110.0)

0.006

Use of venous central line

218 (65.5)

200 (67.8)

0.537

Use of mechanical circulatory support

0.134

 None

138 (41.4)

97 (32.9)

 

 ECMO

126 (37.8)

127 (43.1)

 

 IABP

51 (15.3)

48 (16.3)

 

 ECMO + IABP

18 (5.4)

23 (7.8)

 

Shock-to-ECMO time < 24 h

126 (37.8)

133 (45.1)

0.066

ECPR

62 (18.6)

72 (24.4)

0.077

Continuous renal replacement therapy

75 (22.5)

109 (36.9)

 < 0.001

Mechanical ventilation

219 (65.8)

198 (67.1)

0.720

Length of intensive care unit stay (day)

8.0 (4.0–16.5)

6.0 (2.0–15.0)

0.002

Length of hospital stay (day)

14.0 (8.0–28.0)

11.0 (5.0–27.0)

0.001

  1. Values are shown as n (%) or median (interquartile range)
  2. ECMO extracorporeal membrane oxygenation, ECPR extracorporeal cardiopulmonary resuscitation, IABP intra-aortic balloon pump, Nt-proBNP N-terminal pro B-type natriuretic peptide