Table 1 Demographics and clinical characteristics of patients with DNSAs in the training cohort
Predictors | All (n = 363) | Airway management | p | |
|---|---|---|---|---|
Yes (n = 60) | No (n = 303) | |||
Age, median (IQR), years | 51.0 (37.0–61.0) | 61.5 (54.0–67.0) | 47.0 (35.0–58.0) | < 0.001 |
Sex, male, n (%) | 246 (67.8) | 41 (68.3) | 205 (67.7) | 0.918 |
Antibiotic allergy, n (%) | 29 (8.0) | 5 (8.3) | 24 (7.9) | 0.915 |
Disease duration, median (IQR), days | 7.0 (4.0–11.0) | 7.0 (5.0–11.8) | 7.0 (4.0–11.0) | 0.344 |
Smoking, n (%) | 90 (24.8) | 14 (23.3) | 76 (25.1) | 0.774 |
Alcoholism, n (%) | 30 (8.3) | 6 (10.0) | 24 (7.9) | 0.608 |
Body temperature, median (IQR), °C | 36.6 (36.4–36.9) | 36.6 (36.4–37.0) | 36.6 (36.4–36.8) | 0.335 |
Heart rate, median (IQR), bpm | 86.0 (78.0–99.0) | 90.0 (80.0–110.0) | 85.0 (77.0–97.0) | 0.004 |
Respiratory rate, median (IQR), bpm | 20.0 (18.0–20.0) | 20.0 (18.0–20.8) | 20 (18.0–20.0) | 0.103 |
Diabetes mellitus, n (%) | 94 (25.9) | 26 (43.3) | 68 (22.4) | 0.001 |
Hypertension, n (%) | 51 (14.0) | 14 (23.3) | 37 (12.2) | 0.024 |
Multispace involvement, n (%) | 168 (46.3) | 55 (91.7) | 113 (37.3) | < 0.001 |
Gas formation, n (%) | 99 (27.3) | 43 (71.7) | 56 (18.5) | < 0.001 |
Initial onset of symptoms and signs | ||||
 Pharyngalgia, n (%) | 241 (66.4) | 46 (76.7) | 195 (64.4) | 0.065 |
 Odynophagia, n (%) | 198 (54.5) | 40 (66.7) | 158 (52.1) | 0.039 |
 Neck pain, n (%) | 239 (65.8) | 38 (63.3) | 201 (66.3) | 0.654 |
 Neck swelling, n (%) | 216 (59.5) | 36 (60.0) | 180 (59.4) | 0.932 |
 Dysphagia, n (%) | 133 (36.6) | 34 (56.7) | 99 (32.7) | < 0.001 |
 Trismus, n (%) | 78 (21.5) | 13 (21.7) | 65 (21.5) | 0.971 |
 Hoarseness, n (%) | 23 (6.3) | 9 (15.0) | 14 (4.6) | 0.006 |
 Dyspnea, n (%) | 45 (12.4) | 25 (41.7) | 20 (6.6) | < 0.001 |
Primary regions of infection | ||||
 Suprahyoid region, n (%) | 248 (68.3) | 46 (76.7) | 202 (66.7) | 0.128 |
 Infrahyoid region, n (%) | 78 (21.5) | 1 (1.7) | 77 (25.4) | < 0.001 |
 Retropharyngeal region, n (%) | 37 (10.2) | 13 (21.7) | 24 (7.9) | 0.001 |
Laboratory test | ||||
 NEUT, median (IQR), % | 80.9 (72.9–86.5) | 87.0 (84.2–90.5) | 78.9 (71.3–84.9) | < 0.001 |
 PLR, median (IQR) | 179.1 (132.3–244.7) | 232.5 (182.2–351.5) | 171.8 (124.0–226.7) | < 0.001 |
 RBC, median (IQR), 1012/L | 4.6 (4.2–5.0) | 4.5 (4.1–4.9) | 4.6 (4.3–5.0) | 0.143 |
 Hb, median (IQR), g/L | 135.0 (124.0–146.0) | 133.0 (117.0–145.8) | 136.0 (126.0–146.0) | 0.362 |
 Blood glucose, median (IQR), mmol/L | 6.0 (5.1–9.2) | 8.3 (6.1–13.5) | 5.8 (5.0–8.0) | < 0.001 |
 Albumin, median (IQR), g/L | 38.4 (33.8–42.6) | 31.9 (27.0–36.2) | 39.1 (35.9–43.1) | < 0.001 |