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Table 2 Outcomes of septic patients grouped by the status of premorbid beta-blocker usage

From: Premorbid β1-selective (but not non-selective) β-blocker exposure reduces intensive care unit mortality among septic patients

Variables

Nonusers

n= 1053

Nonselective BB

n= 72

β1-selective BB

n= 137

P value

Fluid infusion, L/24h

5.32±5.57

4.33±4.08

4.33±4.74

0.055

Norepinephrine use

485(46.1%)§

25(34.7%)

47(34.4%)†

0.008

Lactate, 0 h, mg/dL

25.25±27.67§

18.84±19.85

18.04±15.32†

0.004

Lactate, 6 h, mg/dL

24.18±26.40§

19.59±20.18

16.13±12.16†

0.001

Ventilator use, days

13.60±34.23

13.13±13.29

14.44±19.74

0.956

Long term ventilator use (n, %)

61(5.8%)

4(5.6%)

8(5.8%)

0.996

Length of ICU stay, days

9.82±6.90

11.29±8.51

10.81±7.73

0.087

ICU mortality (n, %)

217(20.6%)§

11(15.3%)

13(9.5%)†

0.005

  1. Significant difference (P<0.05) compared to the nonusers group
  2. Significant difference (P<0.05) compared to the nonselective BB group
  3. §Significant difference (P<0.05) compared to the β1-selective BB group
  4. BB β-blocker, ICU intensive care unit