Fig. 3
From: A novel mouse model of heatstroke accounting for ambient temperature and relative humidity
Effect of oral rehydration solution intake on body weight and histopathological findings of organ tissues. a Rate of weight loss (NT, water, ORS): The body weight of animals in the NT group was significantly reduced immediately and 6 h after exposure to heat (*p < 0.05). The use of water and oral solution had similar impact on the animals. b Hepatic vacuolation improved but remained present in the water group. Concurrently, there were very few formations in the oral rehydration solution group. c Intestinal tissue specimens from NT animals were marked with intestinal epithelial erosions (arrow) and swelling of the intestinal villi. Intestinal tissue specimens in the ORS showed only minor damage. d Renal tissue specimens in the NT group showed degeneration of the tubular epithelial cells (arrow) and urinary casts (asterisk). However, no damage was observed in the specimens acquired from the water and oral rehydration solution groups. NT, no treatment; ORS, oral rehydration solution; V, central vein