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Fig. 2 | Journal of Intensive Care

Fig. 2

From: A novel mouse model of heatstroke accounting for ambient temperature and relative humidity

Fig. 2

Histopathological findings of organ specimens collected after heat exposure. a Vacuolar hepatocytes (arrow) appeared around the hepatic central vein in the specimens of the animals exposed to the ambient temperature of 41 °C. P, portal vein; V, central vein. b Kidney specimens of the group exposed to the ambient temperature of 41 °C showed mild swelling and degeneration of tubular epithelial cells (arrow) and urinary casts (asterisk). c The intestinal structures of the group exposed to the ambient temperature of 41 °C were severely destroyed. The mucosal epithelial cells were eroded (arrow), and the intestinal villi showed interstitial edema (arrowhead). d No significant between-group differences were observed in the lung specimens of the group exposed to the ambient temperature of 37 °C and of that exposed to the ambient temperature of 41 °C

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