Table 1 Clinical characteristics of patients with septic shock in the presence or absence of acute respiratory distress syndrome (ARDS)
Characteristic | All septic shock patients (n=38) Median (IQR) or n (%) | Septic shock patients with ARDS (n=20) Median (IQR) or n (%) | Septic shock patients without ARDS (n=18) Median (IQR) or n (%) | P value |
|---|---|---|---|---|
Age, years | 75 (67, 81) | 78 (68, 82) | 72 (64, 79) | 0.396 |
Male | 28 (73) | 14 (70) | 14 (78) | 0.257 |
ICU stay, days | 9 (7, 15) | 10 (8, 17) | 9 (5, 11) | 0.026 |
Site of infection | ||||
 Intra-abdominal | 15 (40) | 7 (35) | 8 (44) | 0.793 |
 Respiratory tract | 6 (16) | 3 (15) | 3 (17) | 1.0 |
 Urinary tract | 10 (26) | 6 (30) | 4 (22) | 0.719 |
 Skin/soft tissue | 3 (8) | 1 (5) | 2 (11) | 0.595 |
 Others | 4 (9) | 3 (15) | 1 (6) | 0.606 |
Nonhospital health care-associated infection | 11 (29) | 6 (30) | 5 (28) | 0.836 |
Bacteria | ||||
 Gram-positive | 14 (37) | 7 (35) | 7 (39) | 0.929 |
 Gram-negative | 18 (47) | 10 (50) | 8 (44) | 0.986 |
 Both | 4 (11) | 2 (10) | 2 (11) | 1.0 |
Fungus | 2 (5) | 1 (5) | 1 (6) | 1.0 |
Maximum SOFAa | 11 (9, 15) | 14 (9, 17) | 9 (7, 11) | 0.202 |
APACHE II scoreb | 30 (26, 34) | 32 (28, 35) | 30 (26, 31) | 0.063 |
Presence of comorbidities | 16 (42) | 7 (35) | 9 (50) | 0.544 |
Surgical intervention | 16 (42) | 6 (30) | 10 (56) | 0.206 |
Mechanical ventilation | 22 (58) | 20 (100) | 2 (11) | <0.001 |
ICU deaths | 1 (2.6) | 1 (5) | 0 (0) | 1.0 |
Syn-1, ng/ml | 265 (168, 494) | 423 (193, 826) | 177 (168, 494) | <0.001 |