|
Study
|
Age (years)
|
Male (%)
|
BMI (kg/m2)
|
DM (%)
|
Hypertension (%)
|
Malignancy (%)
|
Previous VTE (%)
|
Platelet count (× 109/L)
|
D-dimer (mg/L)
|
Patients intubated (%)
|
Patients on inotropes (%)
|
Patients on RRT (%)
|
Patients on ECMO (%)
|
|---|
|
Beun et al. [12]
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
|
Desborough et al. [13]
|
59 (49–66)
|
72.7
|
28 (24–34)
|
40.9
|
45.5
|
7.6
|
7.6
|
207 (154–272)
|
2.4 (1.1–6.2)
|
78.8
|
47
|
27.3
|
12.1
|
|
Fraissé et al. [14]
|
61 (55–70)
|
79.3
|
30 (26–35)
|
38
|
64.1
|
NR
|
5.4
|
227 (182–307)
|
2.4 (1.7–7.9)
|
89.1
|
62
|
23.9
|
NR
|
|
Grandmaison et al. [15]
|
NR
|
72.1
|
NR
|
NR
|
NR
|
6.9
|
6.9
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
|
Helms et al. [16]
|
63 (53–71)
|
81.3
|
NR
|
20
|
NR
|
6
|
5.3
|
200 (152–267)
|
2.3 (1.2–20)
|
100
|
NR
|
NR
|
8
|
|
Hippensteel et al. [17]
|
56 ± 16
|
58.2
|
32.4 ± 9.9
|
30.8
|
NR
|
3.3
|
NR
|
200 ± 91
|
3.0 ± 10.3
|
84.6
|
67
|
NR
|
NR
|
|
Klok et al. [18]
|
64 ± 12
|
75.5
|
NR
|
NR
|
NR
|
2.7
|
NR
|
NR
|
NR
|
NR
|
NR
|
12.5
|
NR
|
|
Llitjos et al. [19]
|
68 (52–75)
|
76.9
|
30.2 (25.5–33.5)
|
NR
|
84.6
|
0
|
3.8
|
234 (169–306)
|
1.8 (1.1–2.9)
|
100
|
88.5
|
15.4
|
7.7
|
|
Lodigiani et al. [20]
|
61 (55–69)
|
80.3
|
NR
|
18
|
42.6
|
3.3
|
0
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
|
Maatman et al. [21]
|
61 ± 16
|
56.9
|
34.8 ± 11.8
|
39.4
|
67.9
|
NR
|
NR
|
207 (152–255)
|
0.5 (0.3–1.0)
|
94.5
|
64.2
|
14.7
|
2.8
|
|
Middeldorp et al. [22]
|
62 ± 10
|
77.3
|
27 (24–29)
|
NR
|
NR
|
4
|
2.7
|
251 ± 89
|
2 (0.8–8.1)
|
NR
|
NR
|
NR
|
NR
|
|
Poissy et al. [23]
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
|
Tavazzi et al. [24]
|
68 ± 7
|
83.3
|
29.3 ± 4.4
|
NR
|
NR
|
NR
|
NR
|
NR
|
NR
|
100
|
NR
|
NR
|
NR
|
|
Thomas et al. [25]
|
NR
|
69.8
|
NR
|
NR
|
NR
|
1.6
|
1.6
|
NR
|
3.9a (1.2–36.3)
|
82.5
|
NR
|
36.5
|
NR
|
- BMI body-mass index, DM diabetes mellitus, CKD chronic kidney disease, VTE venous thromboembolism, RRT renal replacement therapy, ECMO extracorporeal membrane oxygenation, NR not reported
- Unless otherwise stated, all values are represented in percentages (%), mean ± standard deviation, or median (interquartile range)
- aValue represented as median (range)
