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Table 3 Negative MAP changes, in patients with decrease in MAP, after intravenous paracetamol administration

From: Hemodynamic effects of intravenous paracetamol in critically ill children with septic shock on inotropic support

Negative changes

Time after paracetamol administration

30 min

60 min

90 min

120 min

No. of events with ≥ 15% drop in MAP

8 (7.6%)

18 (17.1%)

16 (15.2%)

17 (16.2%)

Mean drop (mmHg)

− 19 ± 4

− 20 ± 7

− 20 ± 5

− 19 ± 5

No. of events with MAP below normal

2 (1.9%)

13 (12.4%)

10 (9.5%)

9 (8.6%)

Mean MAP below normal (mmHg)

− 6 ± 0

− 13 ± 4

− 13 ± 7

− 11 ± 4

  1. MAP mean arterial pressure