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Table 2 Changes in hemodynamic parameters after intravenous paracetamol, whole cohort

From: Hemodynamic effects of intravenous paracetamol in critically ill children with septic shock on inotropic support

ParameterTime after paracetamol administration (no. of doses)p value
0 min (105)30 min (105)60 min (105)90 min (105)120 min (105)
Mean systolic blood pressure (mmHg)113 ± 15112 ± 14108 ± 15109 ± 15111 ± 16p = 0.002
Mean diastolic blood pressure (mmHg)62 ± 1261 ± 1260 ± 1261 ± 1362 ± 13p = 0.25
Mean arterial blood pressure (mmHg)79 ± 1379 ± 1377 ± 1378 ± 1379 ± 13p = 0.14
Mean heart rate (bpm)130 ± 27130 ± 25124 ± 27122 ± 26120 ± 26p = 0.001
VIS12.1 ± 9.512.2 ± 9.512.1 ± 8.912.4 ± 9.312.1 ± 8.7p = 0.53
Mean Δ from lower limit of normal systolic pressure (mmHg)13 ± 2912 ± 148 ± 179 ± 1711 ± 16 
Mean Δ from lower limit of normal diastolic pressure (mmHg)6 ± 145 ± 144 ± 144 ± 165 ± 15 
  1. All values are mean ± SD
  2. VIS vasopressor-inotropic score, Δ delta