Table 1 Demographic and clinical data of inotropic-supported children with septic shock treated with intravenous paracetamol
Characteristics | Value |
|---|---|
Sex (M:F) | 24:21 |
Age (years), mean ± SD (IQR) | 8.9 ± 5.1 (4.9–13) |
Weight (kg), mean ± SD (IQR) | 32.5 ± 21.0 (17–50) |
PICU patient category | |
Surgical | 3 |
Medical | 14 |
Oncological | 28 |
PELOD-2 score, mean ± SD | 9.1 ± 2.1 |
Origin/background of septic shock | |
Fever and neutropenia | 12 |
Abdominal sepsis | 8 |
Pneumonia | 8 |
Urinary tract infection | 4 |
Skin and deep tissue infection | 4 |
Other | 9 |
Causative organism | |
Gram-negative | 22 |
Gram-positive | 8 |
Fungal | 4 |
Negative blood culture | 11 |
Vasopressor inotropic score, mean ± SD | 12.1 ± 9.5 |
Number of paracetamol prescriptions | 105 |
Indication for intravenous paracetamol* | |
Fever (mean 38.6 ± 0.6 °C) | 83 |
Pain | 22 |
Mechanical ventilation | |
Yes | 83 |
No | 22 |
Survived to PICU discharge | |
Yes | 42 |
No | 3 |