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Fig. 8 | Journal of Intensive Care

Fig. 8

From: Molecular diversity of extended-spectrum β-lactamases and carbapenemases, and antimicrobial resistance

Fig. 8

The genomic structure of the class 1 integron of P. aeruginosa NCGM2.S1. The intl gene, which encodes integrase Int1, catalyzes recombination between the attl1 site of the integron and the attC site of an antimicrobial gene cassette [56]. In multidrug-resistant P. aeruginosa NCGM2.S1 [58], three antimicrobial gene cassettes (blaIMP-1, aac(6′)-1ae, and aadA1) are integrated into the region between attI and attC. The Int1 integrase gene, the attI integration site, and qacE partially deleted in the sulI gene, which encodes resistance to sulfonamide are present

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