Table 1 Comparison of various parameters between the sepsis group and the esophagectomy group
All (n = 85) | Sepsis group (n = 45) | Esophagectomy group (n = 40) | P value | |
|---|---|---|---|---|
Age, years | 67 [59–75] | 70 [56–76] | 66 [62–72] | 0.9470 |
Male, n (%) | 51 (60%) | 21 (47%) | 30 (75%) | 0.0078 |
Body Temperature (°C) | ||||
Day 1 | 37.1 [36.7–37.9] | 36.9 [36.5–37.5] | 37.4 [36.9–38.1] | 0.0092 |
Day 2 | 37.2 [36.8–37.7] | 37.1 [36.7–37.6] | 37.3 [36.9–37.8] | 0.0926 |
Day 3 | 37.3 [36.9–37.8] | 37.3 [36.8–37.8] | 37.3 [37.1–37.8] | 0.5998 |
Day4 | 37.0 [36.6–37.4] | 37.1 [36.9–37.4] | 36.8 [36.5–37.2] | 0.0381 |
MAP (mmHg) | ||||
Day 1 | 71 [61–84] | 65 [58–75] | 79 [68–93] | 0.0047 |
Day 2 | 76 [68–86] | 76 [70–86] | 76 [68–88] | 0.8020 |
Day 3 | 88 [75–94] | 85 [74–94] | 89 [76–94] | 0.8903 |
Day 4 | 90 [74–99] | 89 [71–102] | 88 [77–95] | 0.8111 |
Heart rate (/min) | ||||
Day 1 | 93 [85–108] | 93 [83–112] | 94 [87–106] | 0.8395 |
Day 2 | 89 [78–99] | 86 [74–100] | 90 [86–95] | 0.4170 |
Day 3 | 91 [77–103] | 89 [72–106] | 92 [87–101] | 0.4884 |
Day 4 | 89 [74–98] | 88 [74–101] | 86 [78–101] | 0.9632 |
Respiratory rate (/min) | ||||
Day 1 | 22 [20–26] | 22 [20–26] | 23 [20–26] | 0.9368 |
Day 2 | 20 [18–24] | 20 [18–24] | 20 [20–23] | 0.5720 |
Day 3 | 20 [17–24] | 19 [16–24] | 21 [18–24] | 0.1031 |
Day 4 | 20 [18–23] | 21 [18–23] | 20 [19–23] | 0.6380 |
PaO2/FIO2 | ||||
Day 1 | 277 [214–348] | 298 [230–412] | 243 [203–287] | 0.0140 |
Day 2 | 288 [223–353] | 331 [235–444] | 260 [212–308] | 0.0206 |
Day 3 | 258 [210–318] | 305 [229–346] | 231 [207–289] | 0.0101 |
Day 4 | 257 [210–315] | 320 [264–353] | 240 [187–269] | < 0.0001 |
Fluid (mL/h) | ||||
Day 1 | 132 [110–180] | 165 [118–229] | 124 [108–151] | 0.0204 |
Day 2 | 125 [106–148] | 134 [103–167] | 120 [107–132] | 0.1036 |
Day 3 | 111 [100–132] | 110 [95–150] | 110 [100–125] | 0.7830 |
Day 4 | 98 [89–113] | 103 [89–132] | 96 [87–104] | 0.0736 |
sCr (mg/dL) | ||||
Day 1 | 0.80 [0.59–1.16] | 1.11 [0.67–1.92] | 0.72 [0.57–0.82] | 0.0006 |
Day 2 | 0.82 [0.59–1.08] | 0.9 [0.61–1.33] | 0.76 [0.59–0.90] | 0.0978 |
Day 3 | 0.72 [0.59–1.02] | 0.75 [0.6–1.26] | 0.69 [0.53–0.95] | 0.2986 |
Day 4 | 0.63 [0.44–0.86] | 0.70 [0.5–1.23] | 0.61 [0.44–0.76] | 0.1602 |
eGFR (mL/min/1.73 m2) | ||||
Day 1 | 72 [44–93] | 46 [27–85] | 82 [71–97] | < 0.0001 |
Day 2 | 66 [47–92] | 57 [37–85] | 75 [64–94] | 0.0137 |
Day 3 | 74 [54–93] | 69 [38–87] | 85 [62–99] | 0.0501 |
Day 4 | 86 [67–114] | 78 [39–98] | 98 [74–118] | 0.0214 |
uNGAL (ng/mg creatinine) | ||||
Day 1 | 81.1 [26.2–461] | 461.4 [179.5–1893.9] | 27.1 [16.0–64.9] | < 0.0001 |
Day 2 | 66.4 [21.3–311.2] | 310.8 [108.4–1559.0] | 20.6 [11.9–37.7] | < 0.0001 |
Day 3 | 52.4 [26.0–198.1] | 211.5 [93.4–889.9] | 29.4 [16.5–44.5] | < 0.0001 |
Day 4 | 43.8 [26.9–100.5] | 217.7 [39.4–1285.8] | 37.9 [22.1–64.6] | 0.0002 |
CRP (mg/dL) | ||||
Day 1 | 1.7 [0.6–12.2] | 12.1 [5.4–19.2] | 0.6 [0.3–0.8] | < 0.0001 |
Day 2 | 12.0 [8.6–19.6] | 19.0 [10.5–23.7] | 9.7 [8.3–12.0] | < 0.0001 |
Day 3 | 18.5 [12.6–23.8] | 18.2 [12.5–25.9] | 18.8 [14.1–23.6] | 0.9544 |
Day 4 | 14.3 [11.1–19.6] | 13.4 [11.2–16.0] | 14.8 [11–20.4] | 0.5600 |
APACHE II score | 12 [9–14] | 14 [10–18] | 10 [8–12] | < 0.0001 |
SOFA score | ||||
Day 1 | 4 [2–7] | 6 [2–10] | 3 [2–4.3] | 0.0006 |
Day 2 | 3 [2–5] | 4 [2–6] | 2 [2–3] | 0.0323 |
Day 3 | 3 [2–4] | 3.5 [3–5.8] | 3 [2–5.5] | 0.8503 |
Day 4 | 3 [2–5] | 4 [2–5] | 3 [2–4] | 0.5415 |
ICU stay (days) | 8 [5–8] | 6 [3–10] | 8 [8–8] | 0.0043 |