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Table 1 Comparison of various parameters between the sepsis group and the esophagectomy group

From: Correlation between urinary biomarker and organ failure in patients with sepsis and patients after esophagectomy: a prospective observational study

 All (n = 85)Sepsis group (n = 45)Esophagectomy group (n = 40)P value
Age, years67 [59–75]70 [56–76]66 [62–72]0.9470
Male, n (%)51 (60%)21 (47%)30 (75%)0.0078
Body Temperature (°C)
 Day 137.1 [36.7–37.9]36.9 [36.5–37.5]37.4 [36.9–38.1]0.0092
 Day 237.2 [36.8–37.7]37.1 [36.7–37.6]37.3 [36.9–37.8]0.0926
 Day 337.3 [36.9–37.8]37.3 [36.8–37.8]37.3 [37.1–37.8]0.5998
 Day437.0 [36.6–37.4]37.1 [36.9–37.4]36.8 [36.5–37.2]0.0381
MAP (mmHg)
 Day 171 [61–84]65 [58–75]79 [68–93]0.0047
 Day 276 [68–86]76 [70–86]76 [68–88]0.8020
 Day 388 [75–94]85 [74–94]89 [76–94]0.8903
 Day 490 [74–99]89 [71–102]88 [77–95]0.8111
Heart rate (/min)
 Day 193 [85–108]93 [83–112]94 [87–106]0.8395
 Day 289 [78–99]86 [74–100]90 [86–95]0.4170
 Day 391 [77–103]89 [72–106]92 [87–101]0.4884
 Day 489 [74–98]88 [74–101]86 [78–101]0.9632
Respiratory rate (/min)
 Day 122 [20–26]22 [20–26]23 [20–26]0.9368
 Day 220 [18–24]20 [18–24]20 [20–23]0.5720
 Day 320 [17–24]19 [16–24]21 [18–24]0.1031
 Day 420 [18–23]21 [18–23]20 [19–23]0.6380
PaO2/FIO2
 Day 1277 [214–348]298 [230–412]243 [203–287]0.0140
 Day 2288 [223–353]331 [235–444]260 [212–308]0.0206
 Day 3258 [210–318]305 [229–346]231 [207–289]0.0101
 Day 4257 [210–315]320 [264–353]240 [187–269]< 0.0001
Fluid (mL/h)
 Day 1132 [110–180]165 [118–229]124 [108–151]0.0204
 Day 2125 [106–148]134 [103–167]120 [107–132]0.1036
 Day 3111 [100–132]110 [95–150]110 [100–125]0.7830
 Day 498 [89–113]103 [89–132]96 [87–104]0.0736
sCr (mg/dL)
 Day 10.80 [0.59–1.16]1.11 [0.67–1.92]0.72 [0.57–0.82]0.0006
 Day 20.82 [0.59–1.08]0.9 [0.61–1.33]0.76 [0.59–0.90]0.0978
 Day 30.72 [0.59–1.02]0.75 [0.6–1.26]0.69 [0.53–0.95]0.2986
 Day 40.63 [0.44–0.86]0.70 [0.5–1.23]0.61 [0.44–0.76]0.1602
eGFR (mL/min/1.73 m2)
 Day 172 [44–93]46 [27–85]82 [71–97]< 0.0001
 Day 266 [47–92]57 [37–85]75 [64–94]0.0137
 Day 374 [54–93]69 [38–87]85 [62–99]0.0501
 Day 486 [67–114]78 [39–98]98 [74–118]0.0214
uNGAL (ng/mg creatinine)
 Day 181.1 [26.2–461]461.4 [179.5–1893.9]27.1 [16.0–64.9]< 0.0001
 Day 266.4 [21.3–311.2]310.8 [108.4–1559.0]20.6 [11.9–37.7]< 0.0001
 Day 352.4 [26.0–198.1]211.5 [93.4–889.9]29.4 [16.5–44.5]< 0.0001
 Day 443.8 [26.9–100.5]217.7 [39.4–1285.8]37.9 [22.1–64.6]0.0002
CRP (mg/dL)
 Day 11.7 [0.6–12.2]12.1 [5.4–19.2]0.6 [0.3–0.8]< 0.0001
 Day 212.0 [8.6–19.6]19.0 [10.5–23.7]9.7 [8.3–12.0]< 0.0001
 Day 318.5 [12.6–23.8]18.2 [12.5–25.9]18.8 [14.1–23.6]0.9544
 Day 414.3 [11.1–19.6]13.4 [11.2–16.0]14.8 [11–20.4]0.5600
APACHE II score12 [9–14]14 [10–18]10 [8–12]< 0.0001
SOFA score
 Day 14 [2–7]6 [2–10]3 [2–4.3]0.0006
 Day 23 [2–5]4 [2–6]2 [2–3]0.0323
 Day 33 [2–4]3.5 [3–5.8]3 [2–5.5]0.8503
 Day 43 [2–5]4 [2–5]3 [2–4]0.5415
 ICU stay (days)8 [5–8]6 [3–10]8 [8–8]0.0043
  1. The qualitative data are shown as number (percentage) and the quantitative data are shown as medians [interquartile ranges]. APACHE II, acute physiology and chronic health evaluation II; CRP, C-reactive protein: eGFR, estimated glomerular filtration rate; ICU, intensive care unit; MAP, mean arterial pressure; SOFA, sequential organ failure assessment; sCr, serum creatinine; uNGAL, urine neutrophil gelatinase-associated lipocalin
  2. P value, sepsis vs. esophagectomy