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Table 3 Laboratory analyses pre- and post-treatment. Values expressed as median (IQR)

From: The effect of vitamin K on prothrombin time in critically ill patients: an observational registry study

Laboratory analyses

VK group pre-treatment

n = 129

VK group post-treatment

n = 129

Trend

VK group

p value

VK group

Controls pre-treatment

n = 129

Controls post-treatment

n = 129

Trend controls

p value controls

PT-INR

1.50 (1.40–1.60)

1.40 (1.30–1.50)

< 0.001

1.5 (1.4–1.6)

1.4 (1.3–1.6)

0.004

APTT (s)

35 (30–42)

34 (30–42)

0.96

36 (31–41)

34 (30–41)

0.41

Platelets (× 109/L)

158 (121–224)

150 (103–221)

0.008

167 (104–250)

153 (99–209)

< 0.001

Haemoglobin (g/L)

102 (93–113)

102 (94–112)

0.19

108 (95–119)

103 (94–116)

0.002

Fibrinogen (g/L)

4 (2.9–4.6)

4.6 (3.3–5.9)

< 0.001

3.3 (2.3–4.9)

3.8 (2.9–5.1)

< 0.001

CRP (mg/L)

146 (62–245)

181 (106–278)

< 0.001

89 (35–183)

132 (61–232)

< 0.001

Leukocytes (× 109/L)

13 (9–18)

13 (9–18)

0.91

12 (8–17)

11 (9–16)

0.24

  1. VK vitamin K, PT-INR prothrombin time, international normalized ratio, APTT activated partial thromboplastin time, CRP C-reactive protein