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Table 2 Information on troponin measurement in included studies

From: Prevalence and prognostic value of elevated troponins in patients hospitalised for coronavirus disease 2019: a systematic review and meta-analysis

Study Type of Tn assay Manufacturer Upper reference limit Time of measurement Proportion of patients with Tn measurement, no. measured/no. enrolled (%) Frequency of Tn elevation, no. elevated/no. measured (%)
Arcari et al. hs-TnT, hs-TnI Roche, NA 14 ng/L, 35 ng/L Within 24 h of admission 103/111 (92.8) 39/103 (37.9)
Azoulay et al. NA NA NA On ICU admission 343/379 (90.5) 135/343 (39.4)
Barman et al. hs-TnI NA 14 ng/L On admission 607/908 (66.9) 150/607 (24.7)
Bhatla et al. NA NA 0.010 ng/mL On admission 373/700 (53.3) 82/373 (22.0)
Bhatraju et al. NA NA 0.06 ng/mL During first 3 days in ICU 13/24 (54.2) 2/13 (15.4)
Buckner et al. NA NA 0.1 ng/mL During hospitalisation 67/105 (63.8) 13/67 (19.4)
Cipriani et al. hs-TnI NA 32 ng/L for men, 16 ng/L for women On admission and during hospitalisation 109/136 (80.1) On admission, 41/109 (37.6); overall, 46/109 (42.2)
Du et al. TnI NA 0.05 ng/mL On admission 179/179 (100) 41/179 (22.9)
Ferguson et al. NA NA 0.055 ng/mL Within 24 h of admission 45/72 (62.5) 2/45 (4.4)
Franks et al. TnI Abbott 0.03 ng/mL On admission and during hospitalisation On admission, 128/182 (70.3); overall, 143/182 (78.6) On admission, 65/128 (50.8); overall, 80/143 (55.9)
Gottlieb et al. NA NA 0.9 ng/mL On admission 390/1483 (26.3) 87/390 (22.3)
Goyal et al. NA NA 0.5 ng/mL Within 48 h of admission 246/393 (62.6) 11/246 (4.5)
Harmouch et al. TnI NA 0.05 ng/mL On admission 482/560 (86.1) 97/482 (20.1)
He et al. hs-TnI NA NA During stay in ICU 94/94 (100) 35/94 (37.2)
Heberto et al. hs-TnI Beckman 17.5 ng/L On admission 254/254 (100) 64/254 (25.2)
Hu et al. TnI Siemens 0.040 ng/mL On admission 323/323 (100) 68/323 (21.1)
Huang et al. TnT NA 0.13 ng/mL On ICU admission 60/60 (100) 19/60 (31.7)
Karbalai et al. hs-cTnI NA 26 ng/L for men, 11 ng/L for women During hospitalisation 386/386 (100) 115/386 (29.8)
Lala et al. TnI Abbott 0.03 ng/mL Within 24 h of admission 2736/3047 (89.8) 1751/2736 (36.0)
Lazzeri et al. TnT NA 0.028 ng/mL On ICU admission 28/28 (100) 11/28 (39.3)
Li et al. TnI Beckman 0.03 ng/mL On admission 82/82 (100) 13/82 (15.9)
Li et al. hs-TnI Abbott 34.2 ng/L On admission 2068/2699 (76.6) 181/2068 (8.8)
Lombardi et al. NA NA NA Within 24 hours of admission 614/614 (100) 278/614 (45.3)
Lorente-Ros et al. hs-TnI NA 14 ng/L On admission 707/707 (100) 148/707 (20.9)
Lu et al. TnI NA 0.4 ng/mL During stay in ICU 50/72 (69.4) 36/50 (72.0)
Ma K, et al TnI NA 0.034 ng/mL During hospitalisation 84/84 (100) 9/84 (10.7)
Majure et al. TnI, TnI, TnT, hs-TnT Siemens, Siemens, Roche, Roche 0.045 ng/mL, 0.056 ng/mL, 0.01 ng/mL, 19 ng/L Within 48 hours of admission 6247/11,159 (56.0) 1821/6247 (29.1)
Mejía-Vilet et al. TnI NA 0.020 ng/mL On admission 569/569 (100) 86/569 (15.1)
Nguyen et al. hs-TnI NA 22 ng/L On admission 340/356 (95.5) 140/340 (41.2)
Nie et al. hs-TnI Abbott 26.2 ng/L During hospitalisation NA 103/311 (33.1)
Petrilli et al. NA NA 0.1 ng/mL On admission 2510/2729 (92.0) NA
Price-Haywood et al. TnI NA 0.06 ng/mL On admission 1084/1382 (78.4) 270/1084 (24.9)
Qi et al. hs-TnT Roche 14 ng/L On admission 76/267 (28.5) 3/76 (3.9)
Qin et al. hs-TnI, TnI Various Various On admission 1462/6033 (24.2) 95/1462 (6.5)
Raad et al. hs-TnI Beckman 18 ng/L On admission 1020/1044 (97.7) 390/1020 (38.2)
Shah et al. TnI NA 0.05 ng/mL During hospitalisation 309/635 (48.7) 116/309 (37.5)
Shah et al. TnI NA 0.05 ng/mL During hospitalisation 14/26 (53.8) 5/14 (35.7)
Shen et al. TnI Siemens 0.040 ng/mL On admission 325/325 (100) 80/325 (24.6)
Stefanini et al. hs-TnI Beckman 19.6 ng/L On admission 397/397 (100) 130/397 (32.7)
Szekely et al. TnI Abbott 28 ng/L On admission 100/100 (100) 20/100 (20)
Tan et al. hs-TnI Abbott 26.2 ng/L On admission 115/115 (100) 20/115 (17.4)
van den Heuvel et al. hs-TnT Roche 14 ng/L During hospitalisation 47/51 (92.2) 24/47 (51.1)
Wei et al. hs-TnT Roche 14 ng/L On admission 101/103 (98.1) 16/101 (15.8)
Woo et al. hs-TnT, TnI Roche, Siemens 19 ng/L, 0.040 ng/mL On admission NA NA
Xu et al. TnI NA NA On admission 15/15 (100) 1/15 (6.7)
Yang et al. TnI Siemens 0.040 ng/mL On admission 463/463 (100) 45/463 (9.7)
Yu et al. hs-TnI, TnI Abbott, NA 28 ng/L, 0.3 ng/mL During stay in ICU 226/226 (100) 61/226 (27.0)
Zeng et al. TnI NA 0.026 ng/mL On admission 345/416 (82.9) 29/345 (8.4)
Zhang et al. hs-TnT Roche 14 ng/L On admission 135/135 (100) 40/135 (29.6)
Zhao et al. TnI NA 0.01 ng/mL On admission 88/91 (96.7) 3/88 (3.4)
Zhou et al. hs-TnI Abbott 28 ng/L On admission 145/191 (75.9) 24/145 (16.6)
  1. Hs High-sensitivity, ICU Intensive care unit, NA Not available, Tn Troponin
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Journal of Intensive Care

ISSN: 2052-0492