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Table 2 Biceps brachii and rectus femoris muscle atrophy between survivors and non-survivors

From: Upper limb muscle atrophy associated with in-hospital mortality and physical function impairments in mechanically ventilated critically ill adults: a two-center prospective observational study

 

Day 3

Day 5

Day 7

 

n = 43/21*

n = 38/18*

n = 21/15*

Biceps brachii muscle atrophy ratio

   

 Survivors (%)

5.8 (1.7–11.9)

10.8 (2.7–12.1)

12.2 (9.0–13.9)

 Non-survivors (%)

8.0 (3.7–10.1)

14.8 (7.3–17.0)

19.6 (12.5–28.3)

 Univariate analysis p valuea

0.43

0.01

< 0.01

 Multivariate analysis p valueb

0.38

0.01

< 0.01

Rectus femoris muscle atrophy ratio

   

 Survivors (%)

6.1 (0.7–11.5)

11.0 (3.4–18.9)

15.6 (3.3–18.0)

 Non-survivors (%)

11.1 (4.6–17.6)

18.0 (12.2–23.5)

23.9 (20.2–31.3)

 Univariate analysis p valuea

0.32

0.01

< 0.01

 Multivariate analysis p valueb

0.78

0.049

< 0.01

  1. Atrophy ratio was reported as median (interquartile range)
  2. *The number shows survivors/non-survivors in each study day
  3. aUnivariate analysis was conducted comparing the atrophy ratio between survivors and non-survivors
  4. bMultivariate analysis was conducted using age, gender, APACHE II score, and the limb muscle atrophy to evaluate in-hospital mortality. Good fit was confirmed with the Hosmer–Lemeshow test (p = 0.28–0.85), and the c statistics was 0.71–0.93