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Table 2 The summary results of all 23 studies

From: Non-catecholamine vasopressors in the treatment of adult patients with septic shock—evidence from meta-analysis and trial sequential analysis of randomized clinical trials

Results

Primary outcomes

Subgroup analyses

28 days

90 days

ICU

Hospital

Low risk

High risk

VP

VP analogs

AT-II

Refractory shock

Septic shock

RR

0.92

0.95

0.96

1.08

0.91

0.97

0.95

0.91

0.85

0.84

0.94

95% CI lower bound

0.86

0.88

0.77

0.92

0.84

0.83

0.85

0.81

0.69

0.70

0.87

95% CI upper bound

0.99

1.04

1.20

1.27

0.98

1.15

1.06

1.02

1.06

0.998

1.01

P value

0.02*

0.26

0.73

0.35

0.02*

0.75

0.33

0.11

0.14

0.048*

0.11

  1. ICU intensive care unit, VP vasopressin, AT-II angiotensin II, RR relative risk, CI confidence interval, *P < 0.05