Linkage of alterations in systemic iron homeostasis to patients’ outcome in sepsis: a prospective study

Brandtner, Anna; Tymoszuk, Piotr; Nairz, Manfred; Lehner, Georg F.; Fritsche, Gernot; Vales, Anja; Falkner, Andreas; Schennach, Harald; Theurl, Igor; Joannidis, Michael; Weiss, Günter; Pfeifhofer-Obermair, Christa

doi:10.1186/s40560-020-00495-8

Journal of Intensive Care

Table 3 Characteristics of SOFA and SOFA-extended logistic regression models presented in Fig. 3b

From: Linkage of alterations in systemic iron homeostasis to patients’ outcome in sepsis: a prospective study

Model ID	Parameters	P LRT	AIC	C-index
SOFA_1	log10 ferritin, SOFA, sex, age	0,043	60	0.86
SOFA_2	log10 iron, SOFA, sex, age	0,21	63	0.85
SOFA_3	Transferrin, SOFA, sex, age	0,13	62	0.87
SOFA_4	TransfSat, SOFA, sex, age	0,034	60	0.86
SOFA_5	log10 ferritin, log10 iron, SOFA, sex, age	0,13	62	0.86
SOFA_6	log10 ferritin, transferrin, SOFA, sex, age	0,093	62	0.87
SOFA_7	log10 ferritin, TF-Sat, SOFA, sex, age	0,059	61	0.86
SOFA_8	log10 iron, transferrin, SOFA, sex, age	0,16	63	0.87
SOFA_9	log10 iron, TF-Sat, SOFA, sex, age	0,1	62	0.86
SOFA_10	Transferrin, TF-Sat, SOFA, sex, age	0,097	62	0.86
SOFA_11	log10 ferritin, log10 iron, transferrin, SOFA, sex, age	0,18	64	0.86
SOFA_12	log10 ferritin, log10 iron, TF-Sat, SOFA, sex, age	0,11	63	0.87
SOFA_13	log10 ferritin, transferrin, TF-Sat, SOFA, sex, age	0,12	63	0.87
SOFA_14	log10 iron, transferrin, TF-Sat, SOFA, sex, age	0,2	64	0.86
SOFA	SOFA, sex, age	NA	62	0.84
SAPSII_1	log10 ferritin, SAPSII, sex, age	0,041	61	0.88
SAPSII_2	log10 iron, SAPSII, sex, age	0,28	64	0.86
SAPSII_3	Transferrin, SAPSII, sex, age	0,091	62	0.87
SAPSII_4	TransfSat, SAPSII, sex, age	0,049	61	0.87
SAPSII_5	log10 ferritin, log10 iron, SAPSII, sex, age	0,12	63	0.88
SAPSII_6	log10 ferritin, transferrin, SAPSII, sex, age	0,071	62	0.88
SAPSII_7	log10 ferritin, TF-Sat, SAPSII, sex, age	0,068	62	0.88
SAPSII_8	log10 iron, transferrin, SAPSII, sex, age	0,16	63	0.87
SAPSII_9	log10 iron, TF-Sat, SAPSII, sex, age	0,13	63	0.87
SAPSII_10	Transferrin, TF-Sat, SAPSII, sex, age	0,11	63	0.87
SAPSII_11	log10 ferritin, log10 iron, transferrin, SAPSII, sex, age	0,15	64	0.88
SAPSII_12	log10 ferritin, log10 iron, TF-Sat, SAPSII, sex, age	0,11	63	0.88
SAPSII_13	log10 ferritin, transferrin, TF-Sat, SAPSII, sex, age	0,13	63	0.88
SAPSII_14	log10 iron, transferrin, TF-Sat, SAPSII, sex, age	0,22	65	0.88
SAPSII	SAPSII, sex, age	NA	63	0.85

FT ferritin, TF transferrin, TF-Sat transferrin saturation, Iron serum iron

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ISSN: 2052-0492

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